Results 211 to 220 of about 166,885 (311)

Real‐World Effectiveness and 12‐Month Persistence of a Semaglutide‐Supported Digital Weight‐Loss Service: A Retrospective Cohort Study in Germany

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To evaluate the 12‐month effectiveness and patient persistence of a semaglutide‐supported digital weight‐loss service (DWLS) in a real‐world German cohort. Methods This retrospective study analysed 4535 patients who initiated the Juniper Germany DWLS. Primary endpoints included 12‐month medication and data submission adherence (receiving ≥ 
Louis Talay, Jason Hom, Marilyn Tan, Neera Ahuja   +3 more
wiley   +1 more source

Drinking Patterns and CT/MRI Feature-Based Nomogram Models Can More Accurately Predict Acute Alcoholic Pancreatitis Recurrence. [PDF]

Alcohol Clin Exp Res (Hoboken)
Zhong XY, Peng R, Deng Y, Zhang T, Tang CH, Zhou MT, Ji YF, Li XH, Li BF, Zhang XM.   +9 more
europepmc   +1 more source

Tirzepatide for Obesity in Adults ≥ 65 Years: A Post Hoc Analysis of the SURMOUNT and SUMMIT Clinical Trials

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Tirzepatide is a once‐weekly glucagon‐like peptide‐1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonist (RA) approved for weight management in adults with obesity. Data on older adults remain limited, however. This study aimed to examine tirzepatide's safety and efficacy in adults aged ≥ 65 years with obesity ...
Nasreen Alfaris, Robert F. Kushner, Jianghao Li, Kevin L. Chen, Mia Fenimore, Boris Calderon, Adam Stefanski   +6 more
wiley   +1 more source

Case Report: Delayed complications of endovascular treatment of recurrent erosive hemorrhage in necrotizing pancreatitis. [PDF]

Front Surg
Tokarev M, Semenenko I, Zelenskaia A, Komiyukova B, Shibitov V.   +4 more
europepmc   +1 more source

When proteases reshape barriers: Basement membrane remodelling in development, wound healing and tumour progression

The FEBS Journal, EarlyView.
Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre, Guila Dayan, Patricia Rousselle   +2 more
wiley   +1 more source

Severe Acute Pancreatitis Complicated by Guillain-Barré Syndrome in the Intensive Care Unit. [PDF]

ACG Case Rep J
Wang D, Meng X, Ye T, Zhu C.
europepmc   +1 more source

The emerging role of the Hippo signaling pathway in interorgan crosstalk

The FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song, Chaerin Lee, Eek‐hoon Jho   +2 more
wiley   +1 more source

Rural-urban disparities in acute pancreatitis outcomes: A retrospective cohort study using the National Inpatient Sample (2016-2021). [PDF]

Medicine (Baltimore)
Rashid F, Jafri KS, Ghosh N, Alamgir M, Saeed H, Ahmad MH, Mando-Dakkak E, Quazi MA, Sohail AH, Sheikh AB.   +9 more
europepmc   +1 more source

Molecular dynamics simulations elucidate the misfolding mechanisms of secretion‐defective pancreatic lipase variants

The FEBS Journal, EarlyView.
Misfolding mutations in pancreatic lipase have been identified as potential contributors of chronic pancreatitis, an inflammatory disease of the human pancreas. Here, we describe the effect of these misfolding mutations on pancreatic lipase structure using molecular dynamics simulations and structural modeling.
Gyula Hoffka, András Szabó
wiley   +1 more source

Severe hypertriglyceridemia during pregnancy in a hypothyroid patient: A case report and literature review. [PDF]

SAGE Open Med Case Rep
Abdelmahmuod EA, Elhaj MF, Ibrahim SI, Bashir S, Elouzi E.   +4 more
europepmc   +1 more source