Allosteric inhibition of muscle-type nicotinic acetylcholine receptors by a neuromuscular blocking agent pancuronium. [PDF]
Muscle relaxants are indispensable for surgical anesthesia. Early studies suggested that a classical non-depolarizing muscle relaxant pancuronium competitively binds to the ligand binding site to block nicotinic acetylcholine receptors (nAChR). Our group
Souhei Sakata, Fumihito Ono
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Pancuronium Bromide for Chemical Immobilization of Adult Nile Crocodiles (Crocodylus niloticus): A Field Study [PDF]
(1) Background: Pancuronium bromide is a neuromuscular blocker used for immobilizing crocodiles that can be reversed with neostigmine. A recommended drug dose has only been established for saltwater crocodiles (Crocodylus porosus), mostly based on trials
Lionel Schilliger +6 more
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The Use of Cisatracurium in Cardiac Surgery [PDF]
The introduction of neuromuscular blockers (NMBs) has revolutionized the practice of general anaesthesia, ushering in a new era where anaesthesia is conceptualized as a triad comprising narcosis, analgesia, and muscle relaxation.
Vikas C. Roy, Sakshi Mehta, Rajni Bala
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BACKGROUND AND OBJECTIVES: The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental ...
Angélica de Fátima Braga +4 more
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Use of Neuromuscular Blocking Agents in Elderly Patients: A Narrative Review in Geriatric Medicine [PDF]
Paweł Radkowski,1– 3 Maciej Szewczyk,4 Tariq Dabdoub,1 Rubie Murthy,1 Łukasz Grabarczyk5 1Department of Anesthesiology and Intensive Care, Faculty of Medicine, Collegium Medicum University of Warmia and Mazury, Olsztyn, Poland ...
Radkowski P +4 more
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Drug-induced hearing disorders: a disproportionality analysis of the FAERS database [PDF]
BackgroundTo evaluate and identify reports of adverse events related to hearing impairment with drugs approved in the past 20 years, to identify new adverse reaction signals related to hearing impairment that have not yet been reported, and to improve ...
Baojian Li, Xiaoling Hu, Zichen Yue
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Association between levobupivacaine and pancuronium. Interference in neuromuscular transmission and blockade in rats [PDF]
PURPOSE: To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro. METHODS: Thirty rats were distributed into groups (n = 5) according to the drug used alone or in combination:
Vanessa Henriques Carvalho +5 more
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Effects of the ultra-short-acting beta-blocker Esmolol infusion on cardiovascular parameters and quality of postoperative recovery in patients scheduled for elective plastic surgery [PDF]
Background/Aim: Esmolol is an ultra-short-acting, easily titratable b-adrenergic receptor antagonist used for urgent treatment of hypertension and tachycardia in non-surgical and surgical settings.
Lončar-Stojiljković Dragana
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