Indian Journal of Anaesthesia, 2015 Background and Aims: Local anaesthetics are drugs that are widely used in clinical practice. However, the effects of these drugs on the neuromuscular junction and their influence on the blockade produced by non-depolarising neuromuscular blocking drugs ...
Angelica de Fátima de Assunção Braga +5 more
doaj +2 more sources
DOSE-RESPONSE RELATION FOR ATRACURIUM, ORG NC45 AND PANCURONIUM
British Journal of Anaesthesia, 1982 The potencies of atracurium, Org NC 45 and pancuronium were determined using cumulative dose-response curves. The effective doses producing 95% twitch depression were 279 microgram kg-1, 56 microgram kg-1 and 64 microgram kg-1 respectively, the relative ...
Lars Gramstad, Per Lilleaasen
openalex +2 more sources
Effect of Pancuronium on Plasma Free-Norepinephrine and Epinephrine in Adult Cardiac Surgical Patients [PDF]
, 1978 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65996/1/j.1399-6576.1978.tb01318.x ...
Kothary, S. P. +2 more
core +2 more sources
Allosteric inhibition of muscle-type nicotinic acetylcholine receptors by a neuromuscular blocking agent pancuronium. [PDF]
PLoS One, 2023 Muscle relaxants are indispensable for surgical anesthesia. Early studies suggested that a classical non-depolarizing muscle relaxant pancuronium competitively binds to the ligand binding site to block nicotinic acetylcholine receptors (nAChR). Our group
Sakata S, Ono F.
europepmc +2 more sources
Lethal Injection for Execution: Chemical Asphyxiation? [PDF]
PLoS Medicine, 2007 Data from executions in the US suggest that current lethal injection protocols do not effect death through the mechanisms intended, and that potentially aware inmates could die through pancuronium-induced ...
Brodie +33 more
core +5 more sources
Pancuronium Bromide for Chemical Immobilization of Adult Nile Crocodiles (Crocodylus niloticus): A Field Study. [PDF]
Animals (Basel), 2023 (1) Background: Pancuronium bromide is a neuromuscular blocker used for immobilizing crocodiles that can be reversed with neostigmine. A recommended drug dose has only been established for saltwater crocodiles (Crocodylus porosus), mostly based on trials
Schilliger L +6 more
europepmc +2 more sources
Receptor subunit compositions underly distinct potencies of a muscle relaxant in fast and slow muscle fibers. [PDF]
Front Physiol, 2022 A line of studies in the 1960s–1980s suggested that muscle relaxants do not work uniformly on all skeletal muscles, though its mechanism has not been clarified.
Yamashita M +4 more
europepmc +2 more sources
Effects of the ultra-short-acting beta-blocker Esmolol infusion on cardiovascular parameters and quality of postoperative recovery in patients scheduled for elective plastic surgery [PDF]
Scripta Medica, 2021 Background/Aim: Esmolol is an ultra-short-acting, easily titratable b-adrenergic receptor antagonist used for urgent treatment of hypertension and tachycardia in non-surgical and surgical settings.
Lončar-Stojiljković Dragana
doaj +1 more source
THE EFFECT OF PANCURONIUM BROMIDE AS A MUSCLE RELAXANT ALONE OR COMBINATION WITH DIAZEPAM IN SHEEP [PDF]
Basrah Journal of Veterinary Research, 2008 The effect of pancuronium bromide (0.025 mg/kg. B.W.) alone or combined with diazepam (1mg/Kg. I.V) were evaluated in six adult ewes. Pancuronium bromide alone exhibited a muscle relaxants effect, but without analgesia.
Abdalbari A. Alfars
doaj +1 more source
Revista Brasileira de Anestesiologia, 2015 BACKGROUND AND OBJECTIVES: The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental ...
Angélica de Fátima Braga +4 more
doaj +3 more sources