Results 51 to 60 of about 13,121 (248)

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

Effect of Priming with Atracurium or Pancuronium on the Onset Time of Pancuronium in Patients Undergoing General Anesthesia for Elective Surgery: A Randomised Controlled Trial

Nigerian Postgraduate Medical Journal
Background: Suxamethonium, a rapid-acting muscle relaxant, has been conventionally preferred during rapid sequence induction (RSI). The priming principle, which uses non-depolarising muscle relaxants, is an alternative in situations where it is ...
Thankgod Chukwunnonso Okonkwo, Tinuola Abiodun Adigun, Olusola Kayode Idowu   +2 more
doaj   +1 more source

Analysis of drug-induced hearing loss by using a spontaneous reporting system database.

PLoS ONE, 2019
Many drugs can cause hearing loss, leading to sensorineural deafness. The aim of this study was to evaluate the risk of drug-induced hearing loss (DIHL) by using the Japanese Adverse Drug Event Report (JADER) database and to obtain profiles of DIHL onset
Mizuki Tanaka, Shiori Hasegawa, Satoshi Nakao, Kazuyo Shimada, Ririka Mukai, Kiyoka Matsumoto, Mitsuhiro Nakamura   +6 more
doaj   +1 more source

Mechanical Stimulation via Muscle Activity Is Necessary for the Maturation of Tendon Multiscale Mechanics During Embryonic Development

Frontiers in Cell and Developmental Biology, 2021
During embryonic development, tendons transform into a hypocellular tissue with robust tensile load-bearing capabilities. Previous work suggests that this mechanical transformation is due to increases in collagen fibril length and is dependent on ...
Benjamin E. Peterson, Rebecca A. Rolfe, Allen Kunselman, Paula Murphy, Spencer E. Szczesny, Spencer E. Szczesny   +5 more
doaj   +1 more source

Increase in Ia Afferent Synaptic Excitation of SOD1 G93A Mouse Motoneurons by 2‐Week Anodal Trans‐Spinal Direct Current Stimulation Does Not Ameliorate the Cellular Burden of the Disease

European Journal of Neuroscience, Volume 62, Issue 12, December 2025.
In the presymptomatic SOD1 G93A mouse model of ALS, spinal motoneuron (MN) synaptic excitation is reduced due to disruptions in the postsynaptic elements of Ia synapses. Two weeks of anodal tsDCS were applied to SOD1 G93A animals to modulate MN synaptic excitation levels.
T. Jankowiak, M. Cholewiński, K. Kryściak, E. Krok, K. Grycz, M. Bączyk   +5 more
wiley   +1 more source

The tof-guard neuromuscular transmission monitor and its use in horses O monitor da transmissão neuromuscular "tof-guard" e seu uso em eqüinos

Ciência Rural, 1999
It has been emphasized in the human medical literature, that when using a neuromuscular blocking agent, it is of vital importance the monitoring of the neuromuscular block and that these agents should never be used without it.
Juliana Noda Bechara, Denise Tabacchi Fantoni, Paulo Sergio de Moraes Barros, Elton Rodrigues Migliati, Marcio Augusto Ferreira, Luis Claudio Lopes Correia da Silva   +5 more
doaj   +1 more source

Astrocytic Connexin43 Channels Are Essential for Breathing Pattern Stabilization in the preBötzinger Complex

CNS Neuroscience &Therapeutics, Volume 31, Issue 11, November 2025.
Both pharmacological blockade and genetic knockdown of astrocytic connexin43 channels in the preBötzinger complex induce a high‐frequency breathing pattern, thereby enhancing respiratory motor output. This effect is mediated by astrocytic activation and subsequent ATP release, which activates P2Y1 receptors on somatostatin‐expressing preBötzinger ...
Xue Zhao, Luo Shi, Yongqiang Chen, Hongxiao Yu, Xiaoyi Wang, Xinyi Jing, Tianjiao Deng, Ke Zhao, Xiang Zhang, Yixian Liu, Fang Yuan, Sheng Wang   +11 more
wiley   +1 more source

Early Activation of Children Operated on under Extracorporeal Circulation

Общая реаниматология, 2008
Objective: to study the safety and clinical and economic efficiency of early activation of children operated on under extracorporeal circulation (EC). Subjects and methods.
P. R. Dudov, I. A. Kozlov
doaj   +1 more source

Simulated microgravity exposure markedly attenuates the baroreflex total loop gain and induces orthostatic hypotension in male rats

Physiological Reports, Volume 13, Issue 21, November 2025.
Abstract Autonomic dysfunction is recognized as the central mechanism of orthostatic hypotension after microgravity exposure. Because the arterial baroreflex regulates arterial pressure (AP) via sympathetic nerve activity (SNA), we investigated the systematic baroreflex function under simulated microgravity by conducting an open‐loop analysis.
Kazuhiro Kamada, Hiroshi Mannoji, Takeshi Tohyama, Takuya Nishikawa, Hiroyuki Tsutsui, Kenji Sunagawa, Keita Saku   +6 more
wiley   +1 more source

Effects of Atracurium and Pancuronium on Intraocular Pressure

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2008
Introduction: Cataract is an opacified lens and senile cataract is a common disorder. It is desirable to reduce intraocular pressure (IOP) in order to minimize intra and post operative difficulties and complications.
MR Besharati, V Ayatollahi, AM Miratashi, Sh Behdad   +3 more
doaj