Results 61 to 70 of about 13,121 (248)

Mobitz Type II Atrioventricular Block Followed by Remifentanil in a Patient with Severe Aortic Stenosis

Case Reports in Anesthesiology, 2013
Opioids have been considered for their hemodynamic stability. Remifentanil is an opioid analgesic with rapid metabolism and fast primary effect and recovery. In this paper, a very rare effect of using remifentanil along with propofol was presented. An 84-
Mehryar Taghavi Gilani, Majid Razavi
doaj   +1 more source

Delayed-Onset Malignant Hyperthermia in Association with Rocuronium Use [PDF]

, 2012
Purpose Two cases of malignant hyperthermia suspected to be related to the use of a nondepolarizing neuromuscular blocker are reported. Summary A pharmacogenetic disorder that may occur in as many as 1 in 3000 anesthesia procedures, malignant ...
Beggs, Ashton E., McCann, Jennifer Quinn, Powers, Jan M.   +2 more
core   +2 more sources

Brain‐Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety‐Like Behaviors in Mice

Advanced Science, Volume 12, Issue 40, October 27, 2025.
J.Liu et al. reveal the complete propagation dynamics of cortical traveling waves, from local circuitry initiation to long‐range propagation, and identify their functional relevance in modulating anxiety‐like behaviors and underlying cellular neuroplasticity in mice.
Jiaming Liu, Jia‐Wen Mo, Xunda Wang, Yinuo Ma, Shile Tian, Qi Wang, Peng‐Li Kong, Ziqi An, Li Ding, Jing Ren, Cheng‐Lin Lu, Chuanjun Tong, Ed X. Wu, Qiu‐gen Hu, Xiong Cao, Yanqiu Feng   +15 more
wiley   +1 more source

GsMTx‐4 inhibits the exercise pressor reflex and the muscle mechanoreflex primarily through TRPC inhibition

The Journal of Physiology, Volume 603, Issue 19, Page 5333-5350, October 1, 2025.
Abstract figure legend In decerebrated rats, injection of the TRPC6 channels antagonist (SAR7334) in the arterial supply of the triceps surae muscles was followed by injection of the TRPC6 and Piezo 2 channels antagonist (GsMTx‐4) to isolate the role of Piezo 2 in evoking the muscle mechanoreflex and exercise pressor reflex. The exercise pressor reflex
Guillaume P. Ducrocq, Laura Anselmi, Kristen Brandt, Jianli Wang, Victor Ruiz Velasco, Marc P. Kaufman   +5 more
wiley   +1 more source

Immunodepletion in xenotransplantation [PDF]

, 1990
Xenograft transplantation is perhaps the most immunologically difficult problem in transplantation today. An overwhelming hyperacute rejection reaction (HAR) occurs within minutes of organ implantation.
A. Casavilla, A. G. Tzakis, A. Oks, A. Oral, B. Banner, Branda R F, Forsgren A, Giles G R, J. Murray, K. Yanaga, L. Makowka, L. Podesta, Langone J J, P. D'andrea, R. Shapiro, R. Watt, S. Wos, T. E. Starzl, Ting A, V. Scantlebury   +19 more
core   +1 more source

Methacholine hyperresponsiveness in mice with house dust mite‐induced lung inflammation is not associated with excessive airway constriction ex vivo

Experimental Physiology, Volume 110, Issue 9, Page 1336-1348, September 1, 2025.
Abstract The role of excessive airway constriction in the hyperresponsiveness to nebulized methacholine in mice with experimental asthma is still contentious. Yet, there have been very few studies investigating whether the increased in vivo response to methacholine caused by experimental asthma is associated with a corresponding increase in ex vivo ...
Andrés Rojas‐Ruiz, Magali Boucher, Cyndi Henry, Louis Gélinas, Rosalie Packwood, Percival Graham, Jorge Soliz, Ynuk Bossé   +7 more
wiley   +1 more source

Network Properties Revealed during Multi-Scale Calcium Imaging of Seizure Activity in Zebrafish. [PDF]

, 2019
Seizures are characterized by hypersynchronization of neuronal networks. Understanding these networks could provide a critical window for therapeutic control of recurrent seizure activity, i.e., epilepsy.
Baraban, Scott C, Liu, Jing
core   +1 more source

Strategies for studying permeation at voltage-gated ion channels [PDF]

, 1991
Voltage-dependent ion channels are presently thought to consist of several distinct functional regions: (a) activation gates, (b) inactivation gates, and permeation pathways.
Lester, Henry A.
core   +1 more source

Inhibition and potentiation of the exercise pressor reflex by pharmacological modulation of TRPC6 in male rats

The Journal of Physiology, Volume 603, Issue 18, Page 5027-5052, September 15, 2025.
Abstract figure legend The majority of L4–L5 dorsal root ganglion cells innervating the triceps surae muscles of healthy rats expressed TRPC6 channels. In decerebrated rats, pharmacological inhibition of TRPC6 channels by injection of antagonists (SAR7334 or BI‐749327) into the arterial supply of the triceps surae muscles inhibited the exercise pressor
Guillaume P. Ducrocq, Laura Anselmi, Salvatore L. Stella Jr, Steven W. Copp, Victor Ruiz‐Velasco, Marc P. Kaufman   +5 more
wiley   +1 more source

Lactate and hydrogen ions play a predominant role in evoking the exercise pressor reflex during ischaemic contractions but not during freely perfused contractions

The Journal of Physiology, Volume 603, Issue 18, Page 5053-5070, September 15, 2025.
Abstract figure legend The role of lactate and hydrogen ions in evoking the metabolic component of the exercise pressor reflex was studied in rats with either a functional pygm gene (pygm+/+) or with a non‐functional “knocked out” pygm gene (pygm−/−). The pygm gene is responsible for producing the myophosphorylase enzyme which catalyses the breakdown ...
Guillaume P. Ducrocq, Laura Anselmi, Victor Ruiz‐Velasco, Marc P. Kaufman   +3 more
wiley   +1 more source