Results 11 to 20 of about 5,405 (217)

GsMTx-4 inhibits the exercise pressor reflex and the muscle mechanoreflex primarily through TRPC inhibition. [PDF]

J Physiol
Abstract figure legend In decerebrated rats, injection of the TRPC6 channels antagonist (SAR7334) in the arterial supply of the triceps surae muscles was followed by injection of the TRPC6 and Piezo 2 channels antagonist (GsMTx‐4) to isolate the role of Piezo 2 in evoking the muscle mechanoreflex and exercise pressor reflex. The exercise pressor reflex
Ducrocq GP, Anselmi L, Brandt K, Wang J, Velasco VR, Kaufman MP.   +5 more
europepmc   +2 more sources

Increase in Ia Afferent Synaptic Excitation of SOD1 G93A Mouse Motoneurons by 2-Week Anodal Trans-Spinal Direct Current Stimulation Does Not Ameliorate the Cellular Burden of the Disease. [PDF]

Eur J Neurosci
In the presymptomatic SOD1 G93A mouse model of ALS, spinal motoneuron (MN) synaptic excitation is reduced due to disruptions in the postsynaptic elements of Ia synapses. Two weeks of anodal tsDCS were applied to SOD1 G93A animals to modulate MN synaptic excitation levels.
Jankowiak T, Cholewiński M, Kryściak K, Krok E, Grycz K, Bączyk M.   +5 more
europepmc   +2 more sources

Simulated microgravity exposure markedly attenuates the baroreflex total loop gain and induces orthostatic hypotension in male rats. [PDF]

Physiol Rep
Abstract Autonomic dysfunction is recognized as the central mechanism of orthostatic hypotension after microgravity exposure. Because the arterial baroreflex regulates arterial pressure (AP) via sympathetic nerve activity (SNA), we investigated the systematic baroreflex function under simulated microgravity by conducting an open‐loop analysis.
Kamada K, Mannoji H, Tohyama T, Nishikawa T, Tsutsui H, Sunagawa K, Saku K.   +6 more
europepmc   +2 more sources

The U.S. Supreme Court is about to re-evaluate how some states carry out lethal injections. [PDF]

, 1975
Next month, the Supreme Court will hear oral arguments in a case which challenges Oklahoma’s use of “liquid fire” in executions. The drug – potassium chloride – is one of a cocktail of drugs currently used in some states to carry out death sentences, a ...
Millar, Nancy E.
core   +3 more sources

Neuromuscular Blockade with Rocuronium Bromide Increases the Tolerance of Acute Normovolemic Anemia in Anesthetized Pigs [PDF]

, 2012
Background: The patient's individual anemia tolerance is pivotal when blood transfusions become necessary, but are not feasible for some reason. To date, the effects of neuromuscular blockade (NMB) on anemia tolerance have not been investigated. Methods:
A. Pape, B. Zwissler, Barton RG, Cain SM, Eisenberg E, Fontana JL, H. Kertscho, Habler OP, Haller M, Herweling A, Holt JP, Ickx BE, Kampe S, Kemming GI, Kim J, Koskolou MD, Levy PS, M. Lossen, Madjdpour C, Marik PE, McCall M, Meier J, Meier JM, Meier JM, Meier JM, Meisner FG, Messmer KF, Muldoon SM, Naguib M, O. Habler, O. Horn, P. Stein, Pape A, Pape A, Pape A, Perez V, Pittman RN, Richardson RS, Russell WC, S. Kutschker, Schumacker PT, van der Linden P, van der Linden P, van Woerkens EC, Vernon DD, Werlhof V, Zollinger A   +46 more
core   +1 more source

Alterations in neuromuscular junction morphology with ageing and endurance training modulate neuromuscular transmission and myofibre composition. [PDF]

J Physiol
Abstract figure legend The morphology and function of the neuromuscular junction (NMJ), the synapse connecting motor neurons and myofibres, change with ageing and exercise training. The age‐related decrease in the overlap between nerve terminal and acetylcholine receptors at the NMJ impaired neuromuscular transmission, as evidenced by the decrease in ...
Yamaguchi T, Kouzaki K, Sasaki K, Nakazato K.   +3 more
europepmc   +2 more sources

Neuro-Protection and Neuro-Therapy Effects of Acalypha indica Linn. Water Extract Ex Vivo on Musculus gastrocnemius Frog

Makara Journal of Health Research, 2010
The studies of neuro-protection and neuro-therapy effects of Acalypha indica Linn. water extract ex vivo on Musculus gastrocnemius frog have already done at three Departments in Faculty of Medicine, University of Indonesia.
Ernie Hernawati Purwaningsih, Nurhadi Ibrahim, Hamdani Zain, Arjo Tedjo   +3 more
doaj   +1 more source

A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]

, 2012
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J, Price, David, Stollenwerk, Nicholas   +2 more
core   +2 more sources

Monitoring of Single-Cell Responses in the Optic Tectum of Adult Zebrafish with Dextran-Coupled Calcium Dyes Delivered via Local Electroporation [PDF]

, 2013
Kassing V, Engelmann J, Kurtz R. Monitoring of Single-Cell Responses in the Optic Tectum of Adult Zebrafish with Dextran-Coupled Calcium Dyes Delivered via Local Electroporation. PLoS ONE.
Engelmann, Jacob , Kassing, Vanessa, Kurtz, Rafael   +2 more
core   +11 more sources

Anestesia peribulbar com ropivacaína como alternativa ao bloqueio neuromuscular para facectomia em cães Peribulbar anesthesia with ropivacaine as an alternative to neuromuscular blocking agents for cataract surgery in dogs

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2010
Desenvolveu-se uma técnica de bloqueio peribulbar comparando-a à técnica de anestesia oftálmica com bloqueio neuromuscular parcial em cães submetidos à facectomia extracapsular.
V.N.L.S. Oliva, A.L. Andrade, L. Bevilacqua, L.M. Matsubara, S.H.V. Perri   +4 more
doaj   +1 more source