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The Adult Respiratory Distress Syndrome and Pancuronium Bromide
The institution and maintenance of artificial ventilation for a patient with the adult respiratory distress syndrome (ARDS) is frequently difficult because the hypoxic patient is often confused, agitated, or combative. Pancuronium bromide, a recently introduced neuromuscular blocking agent, was used to facilitate artificial ventilation in 6 patients ...
Richard W. Light+2 more
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The Fate of Pancuronium Bromide in Man [PDF]
The fate of pancuronium bromide has been investigated in 20 anaesthetized patients, seven undergoing cholecystectomy with choledochostomy (Group I), seven undergoing cholecystectomy only (Group II) and six undergoing pelvic operations (Group III). A fluorimetric method was used to determine pancuronium bromide and its bis‐quaternary derivatives in ...
Dirk K. F. Meijer+3 more
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The Fate of Pancuronium Bromide in the Cat
Acta Anaesthesiologica Scandinavica, 1973The fate of pancuronium bromide has been investigated in the cat. A sensitive fluorimetric method was used to determine pancuronium bromide and its bis‐quaternary metabolites in biological material. After intravenous injection of 0.3 mg/kg pancuronium bromide, the drug disappeared rapidly from plasma in two phases, with half‐lives of 4 and 32 min ...
Sandor Agoston+2 more
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Anaphylaxis with pancuronium bromide
Journal of Medical Society, 2014Anaphylactic reactions occurring during anaesthesia remain a major cause of concern for anaesthesiologists. Serious and occasionally fatal anaphylactic reaction may occur when a patient is exposed to a drug for the first time. On time prompt recognition and treatment of the acute event by the attending anaesthesiologist and subsequent determination of ...
Kulsum+3 more
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Status asthmaticus and pancuronium bromide
Critical Care Medicine, 1972The use of neuromuscular blocking agents as an adjunct to accepted drug therapy in medically irreversible status asthmaticus allows time for the drug therapy to become effective. The accessory muscles of respiration are also relaxed and, therefore, a decrease in oxygen demand by the body occurs.
John B. Dillon, Norman Levin
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The interaction of halothane and pancuronium bromide [PDF]
The interaction of halothane and pancuronium is demonstrated in the dog tibialis anterior-sciatic nerve preparation. The results show a dose related effect of halothane on the recovery index and the 50% recovery times. These results are compared to other reports and possible mechanisms are discussed.
P.K. Barnes, C.L. Knight, S.A. Feldman
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Cardiovascular Effects of Pancuronium Bromide
John B. Dillon, Norman Levin
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