Results 41 to 50 of about 31,298 (246)
A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley +1 more source
Clinical Study of Pancytopenia
Introduction: Pancytopenia is a common and alarming condition encountered by clinicians. We had studied the clinical presentation, laboratory investigations and various etiologies of Pancytopenia. Material and Methods: Study was carried out in a tertiary
Vaidya, Meghna +2 more
core +2 more sources
Introduction: Pancytopenia is said to exist in an adult when the hemoglobin level is less than 13.5gm/dl in males and 1 l.5gm/dlin females, white cell count less than 4xl09IL and platelet count less than 150x109/L1. The causes of pancytopenia are aplastic anemia, subleukemicleukemia, myelodysplasia2 multiple myeloma, nutritional deficiencies leading to
AZIZULLAH JALBANI +5 more
openaire +2 more sources
Rheumatologic Manifestations of Patients With Type B Insulin Resistance
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya +4 more
wiley +1 more source
Citation: 'pancytopenia' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13532 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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ABSTRACT The predictive value of cytokines (CK) for malignancy‐associated adult hemophagocytic lymphohistiocytosis (M‐HLHa) remains uncertain. We evaluated a cytokine‐based Risk Score (RS) and the IL‐10/IL‐6 Ratio to predict M‐HLHa. Adult patients (n = 112) from the French HLH cohort (NCT02113917) with complete data for nine key HLH related CK measured
Coralie Bloch +47 more
wiley +1 more source
Background: Pancytopenia is defined as the simultaneous presence of anemia, leukopenia, and thrombocytopenia. The present study was undertaken to explore various causes and clinical manifestations of pancytopenia and to correlate them with severity of ...
Amit Varma +4 more
doaj +1 more source
Clinico-hematological profile of pancytopenic adult patients in a tertiary care teaching hospital
Objective: The causes of pancytopenia vary in different populations depending on age, gender, nutrition, geographic location, standard of living, and exposure to certain infections and drugs.
Anil Jain +5 more
doaj +1 more source
ABSTRACT Quizartinib is a tyrosine kinase inhibitor with single agent activity in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) and has demonstrated efficacy in first‐line therapy when combined with intensive chemotherapy in both FLT3 ITD‐negative and positive AML.
Teresa Bernal +29 more
wiley +1 more source
Background: Pancytopenia, a severe hematologic comorbidity, raises significant clinical concern for increased morbidity and mortality in people living with HIV (PLWH).
Xiangyi Shen +11 more
doaj +1 more source

