Deep Learning-based structural and functional annotation of Pandoravirus hypothetical proteins
bioRxiv, 2023 Giant viruses, including Pandoraviruses, contain large amounts of genomic ‘dark matter’ - genes encoding proteins of unknown function. New generation, deep learning-based protein structure modelling offers new opportunities to apply structure-based ...
Joseph L. Horder +11 more
semanticscholar +2 more sources
An Update on Eukaryotic Viruses Revived from Ancient Permafrost [PDF]
Viruses, 2023 One quarter of the Northern hemisphere is underlain by permanently frozen ground, referred to as permafrost. Due to climate warming, irreversibly thawing permafrost is releasing organic matter frozen for up to a million years, most of which decomposes ...
Jean-Marie Alempic +11 more
doaj +2 more sources
Genome-wide Characterization of Non-shared Sequences among Amphora-shaped Giant Viruses. [PDF]
Microbes EnvironGiant viruses are distinguished not only by their large particle size, but also by their extensive genomes, often reaching megabase levels. Many sequences within these genomes are considered to have been introduced by hosts, surrounding organisms, or ...
Akashi M, Takemura M, Suzuki S.
europepmc +2 more sources
Nucleic and Amino Acid Sequences Support Structure-Based Viral Classification [PDF]
Journal of Virology, 2017 Viral capsids ensure viral genome integrity by protecting the enclosed nucleic acids. Interactions between the genome and capsid and between individual capsid proteins (i.e., capsid architecture) are intimate and are expected to be characterized by ...
Bamford, Dennis H. +2 more
core +3 more sources
Co-infection of phylogenetically distinct nucleocytoviruses in Acanthamoeba castellanii cells. [PDF]
FEMS Microbiol LettNucleocytoviruses have extraordinarily large double-stranded DNA genome, including a set of highly conserved genes for viral reproduction. Meanwhile, nucleocytoviruses supposedly acquire new genes from cellular organisms and different lineages of ...
Morimoto D +5 more
europepmc +2 more sources
Current Research in Microbial Sciences, 2020 Viruses are the most prodigious repertory of the genetic material on the earth. They are elusive, breakneck, evolutionary life particles that constitute a riveting concealed world.
Sayak Das +4 more
doaj +2 more sources
Evidence of a cellulosic layer in Pandoravirus tegument and the mystery of the genetic support of its biosynthesis [PDF]
, 2019 Pandoraviruses are giant viruses of amoebae with 1 μm-long virions. They have an ovoid morphology and are surrounded by a tegument-like structure lacking any capsid protein nor any gene encoding a capsid protein.
Djamal Brahim Belhaouari +6 more
semanticscholar +2 more sources
Virology Journal, 2018 Nucleo-cytoplasmic large DNA viruses are doubled stranded DNA viruses capable of infecting eukaryotic cells. Since the discovery of Mimivirus and Pandoravirus, there has been no doubt about their extraordinary features compared to “classic” viruses ...
Julien Andreani +4 more
doaj +2 more sources
A spectacular anomaly in the 4-mer composition of the giant pandoravirus genomes reveals a stringent new evolutionary selection process [PDF]
bioRxiv, 2019 The Pandoraviridae is a rapidly growing family of giant viruses, all of which have been isolated using laboratory strains of Acanthamoeba. The genomes of ten distinct strains have been fully characterized, reaching up to 2.5 Mb in size.
O. Poirot +3 more
semanticscholar +2 more sources
Co-Isolation and Characterization of Two Pandoraviruses and a Mimivirus from a Riverbank in Japan
Viruses, 2019 Giant viruses, like pandoraviruses and mimiviruses, have been discovered from diverse environments, and their broad global distribution has been established. Here, we report two new isolates of Pandoravirus spp.
Motohiro Akashi, Masaharu Takemura
exaly +2 more sources