Evolution of giant pandoravirus revealed by CRISPR/Cas9 [PDF]
Nature Communications, 2023 Giant viruses (GVs) are a hotspot of unresolved controversies since their discovery, including the definition of “Virus” and their origin. While increasing knowledge of genome diversity has accumulated, GV functional genomics was largely neglected. Here,
Hugo Bisio +2 more
exaly +6 more sources
Incomplete tricarboxylic acid cycle and proton gradient in Pandoravirus massiliensis : is it still a virus? [PDF]
ISME Journal, 2021 The discovery of Acanthamoeba polyphaga Mimivirus, the first isolated giant virus of amoeba, challenged the historical hallmarks defining a virus. Giant virion sizes are known to reach up to 2.3µm, making them visible by optical microscopy.
Sarah Aherfi +2 more
exaly +12 more sources
DNA transposons have colonized the genome of the giant virus Pandoravirus salinus [PDF]
BMC Biology, 2015 BACKGROUND: Transposable elements are mobile DNA sequences that are widely distributed in prokaryotic and eukaryotic genomes, where they represent a major force in genome evolution.
Cheng Sun +2 more
exaly +8 more sources
Genome Sequences of Two New Pandoravirus Strains Isolated from Brazil and France [PDF]
Microbiology Resource Announcements, 2022 Pandoraviruses are giant viruses of amoebas with a wide range of genome sizes (1.5 to 2.5 Mbp) and 1-μm ovoid viral particles. Here, we report the isolation, genome sequencing, and annotation of two new strains from the proposed family Pandoraviridae ...
Djamal Brahim Belhaouari +2 more
exaly +6 more sources
Evidence of a Cellulosic Layer in Pandoravirus massiliensis Tegument and the Mystery of the Genetic Support of Its Biosynthesis [PDF]
Frontiers in Microbiology, 2019 Pandoraviruses are giant viruses of ameba with 1 μm-long virions. They have an ovoid morphology and are surrounded by a tegument-like structure lacking any capsid protein nor any gene encoding a capsid protein. In this work, we studied the ultrastructure
Djamal Brahim Belhaouari +2 more
exaly +7 more sources
A Puzzling Anomaly in the 4-Mer Composition of the Giant Pandoravirus Genomes Reveals a Stringent New Evolutionary Selection Process [PDF]
Journal of Virology, 2019 International audienceThe Pandoraviridae is a rapidly growing family of giant viruses, all of which have been isolated using laboratory strains of Acanthamoeba.
Sandra Jeudy +2 more
exaly +10 more sources
Pandoravirus Celtis Illustrates the Microevolution Processes at Work in the Giant Pandoraviridae Genomes [PDF]
Frontiers in Microbiology, 2019 With genomes of up to 2.7 Mb propagated in μm-long oblong particles and initially predicted to encode more than 2000 proteins, members of the Pandoraviridae family display the most extreme features of the known viral world.
Matthieu Legendre +2 more
exaly +11 more sources
Continuous year-round isolation of giant viruses from brackish shoreline soils [PDF]
Frontiers in MicrobiologyGiant viruses, categorized under Nucleocytoviricota, are believed to exist ubiquitously in natural environments. However, comprehensive reports on isolated giant viruses remain scarce, with limited information available on unrecoverable strains, viral ...
Motohiro Akashi +2 more
doaj +6 more sources
Kinetic Analysis of Acanthamoeba castellanii Infected with Giant Viruses Quantitatively Revealed Process of Morphological and Behavioral Changes in Host Cells [PDF]
Microbiology Spectrum, 2021 Most virus-infected cells show morphological and behavioral changes, which are called cytopathic effects. Acanthamoeba castellanii, an abundant, free-living protozoan, serves as a laboratory host for some viruses of the phylum Nucleocytoviricota—the ...
Sho Fukaya, Masaharu Takemura
exaly +5 more sources
Evolution of giant pandoravirus from small icosahedral viruses revealed by CRISPR/Cas9
bioRxiv, 2022 Giant viruses (GVs) are a hotspot of unresolved controversies since their discovery, including the definition of “Virus” and the existence of a fourth domain of life1-3. While increasing knowledge of genome diversity has accumulated4, functional genomics
Bisio H +6 more
europepmc +4 more sources