Results 131 to 140 of about 55,287 (292)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Applied SciencesUtilizing phase change materials (PCMs) in passive energy-saving wall panels to regulate indoor temperatures during hot seasons can improve people’s thermal comfort and reduce the energy consumption of air conditioning systems. This study is based on the
Baoshi Jiang, Chen Yang
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
, 2017 The purpose of the ASCA Resistance training for children and youth: Updated Position Stand is to provide clarity and guidance as possible to assist coaches in designing resistance training programs for children and youth at various stages throughout ...
Bird, Stephen P. +3 more
core
Assessing the role of population growth in the climate change impacts on food security in Africa
Discover AgricultureThis study investigates the nexus between climate change, demographic growth, and food security in African countries. Using panel data covering the period 2006–2022 and applying robust econometric techniques including fixed effects, moderation analysis ...
Metila Nke Alexis Claude
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Conditional Performance Measurement Using Portfolio Weights: Evidence for Pension Funds [PDF]
This paper combines the use of portfolio holdings data and conditioning information to create a new performance measure. Our conditional weight-based measure has several advantages. Using conditioning information avoids biases in weight-based measures as
Wayne Ferson, Kenneth Khang
core
Study of the Applications of the Radiant Cooling Panel in Museum Showcases [PDF]
, 2006 The radiant cooling panel was proposed to control the temperature in the showcases to supply a steadier environment for cultural relic preservation.
Yu, L., Hou, H., Wan, X., Chen, H.
core
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source