Results 71 to 80 of about 2,036,098 (361)
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
It is commonly known that the beer industry, like many other companies in the food sector, has been encouraged to improve their sustainability and waste management requirements.
María Cristina Ravanal +3 more
doaj +1 more source
Purpose: Environmental performance and propensity disclosure is important for stakeholders to estimate firms’ incentives in environmental management practices.
Kai Chang
doaj +1 more source
Non-Gaussian dynamic Bayesian modelling for panel data [PDF]
A first order autoregressive non-Gaussian model for analysing panel data is proposed. The main feature is that the model is able to accommodate fat tails and also skewness, thus allowing for outliers and asymmetries. The modelling approach is designed to
Mark F. J. Steel +3 more
core +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
This study examines how financial structure impacts the profitability of banks and financial institutions listed on the New York Stock Exchange (NYSE), one of the largest stock exchanges in the United States, and the National Association of Securities ...
Mehmet Akarçay
doaj +1 more source
Quantile regression with panel data [PDF]
We propose a generalization of the linear quantile regression model to accommodate possibilities afforded by panel data. Specifically, we extend the correlated random coefficients representation of linear quantile regression (e.g., Koenker, 2005; Section 2.6).
Bryan S. Graham +3 more
openaire +3 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
CLUSTER ANALYSIS OF MULTIVARIATE PANEL DATA ON DATA CONTAINING OUTLIERS
One clustering method for panel data is K-Means Longitudinal (KML), which considers only a single trajectory per subject over time. To address this limitation, KML was extended into K-Means Longitudinal 3D (KML3D), which enables clustering of joint or ...
Kristuisno Martsuyanto Kapiluka +2 more
doaj +1 more source

