Results 71 to 80 of about 27,018,147 (310)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Türkiye’de İller Arası Alınan Göç: Çok Boyutlu Panel Veri Analizi
İşletme Bilimi Dergisiİnsanlık tarihi boyunca çeşitli nedenlerden dolayı, insanlar ikamet ettikleri yerleri değiştirmek durumunda kalmışlardır. Mevcut konumundan farklı bir yere gitme durumu, göç kavramını ortaya çıkarmıştır.
Mustafa Ercan Kılıç, Mert Şahin
doaj +1 more source
Quantile regression with panel data [PDF]
, 2015 We propose a generalization of the linear quantile regression model to accommodate possibilities afforded by panel data. Specifically, we extend the correlated random coefficients representation of linear quantile regression (e.g., Koenker, 2005; Section 2.6).
Bryan S. Graham +3 more
openaire +3 more sources
The First Report of the Congressional Oversight Panel for Economic Stabilization
, 2008 December report of the U.S. Congressional Oversight Panel describing their activities and findings regarding the U.S.
United States. Congressional Oversight Panel.
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Nonlinear Panel Data Models [PDF]
, 2008 Panel or longitudinal data are becoming increasingly popular in applied work as they offer a number of advantages over pure cross-sectional or pure time-series data. A particularly useful feature is that they allow researchers to model unobserved heterogeneity at the level of the observational unit, where the latter may be an individual, a household, a
openaire +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Ekonomi, Politika & Finans Araştırmaları DergisiThis study examines how financial structure impacts the profitability of banks and financial institutions listed on the New York Stock Exchange (NYSE), one of the largest stock exchanges in the United States, and the National Association of Securities ...
Mehmet Akarçay
doaj +1 more source
Background Variables LISS panel households
, 2011 These datasets contain the demographics and other general characteristics of LISS panel households, which are measured every month using a separate questionnaire, known as the Household Box.
Das, Prof.dr. J.W.M. (CentERdata - Institute for data collection and research - Tilburg University) DAI=info:eu-repo/dai/nl/137115008 +1 more
core +1 more source