Results 91 to 100 of about 27,018,147 (310)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Predictive Regressions with Panel Data [PDF]

open access: yesSSRN Electronic Journal, 2006
This paper analyzes panel data inference in predictive regressions with endogenous and nearly persistent regressors. The standard fixed effects estimator is shown to suffer from a second order bias; analytical results, as well as Monte Carlo evidence, show that the bias and resulting size distortions can be severe.
openaire   +2 more sources

One-Step Robust Estimation of Fixed-Effects Panel Data Models [PDF]

open access: yes
The panel-data regression models are frequently applied to micro-level data, which often suffer from data contamination, erroneous observations, or unobserved heterogeneity.
Cizek, P., Aquaro, M.
core  

October Oversight Report [PDF]

open access: yes, 2009
October report of the U.S. Congressional Oversight Panel describing their activities and findings regarding the evaluation of the U.S.
United States. Congressional Oversight Panel.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Indonesian Happiness Factor: A Panel Data Analysis

open access: yesJurnal Ekonomi dan Studi Pembangunan
The measurement of welfare level is one of the success benchmarks of a country's developmental program. Welfare assessments in the form of subjective well-being (SWB) can complement the objective measures.
Rakhmawati Rakhmawati
doaj   +1 more source

Treatment Effects and Panel Data [PDF]

open access: yes, 2015
It is a major achievement of the econometric treatment effect literature to clarify under which conditions causal effects are non-parametrically identified. The first part of this chapter focuses on the static treatment model. In this part, I show how panel data can be used to improve the credibility of matching and instrumental variable estimators. In
openaire   +2 more sources

Choosing Between Panel Data Stationarity Tests [PDF]

open access: yes
When testing for stationarity in panel data several tests are available. These tests differ in degree to which they allow for serial correlation in the series under the null hypothesis.
Kristian Jönsson
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy