Results 101 to 110 of about 4,501,132 (351)
This article examines inconsistencies in the assumptions on which the new macroeconomic consensus is based, before going on to propose an alternative theoretical framework for understanding how exchange rate interventions work, and the compensatory ...
Eduardo Rosas Rojas
doaj
Allocentrism and numerator-based innovation: Panel data evidence
We explore the existence of a relationship between firms' allocentric approach, measured by their collaboration activities for innovation, and the orientation of their innovation.
Pedro Mendi, Alejandro Ruelas-Gossi
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
We present a flexible approach to the identification and estimation of causal objects in nonparametric, non-separable models with confounding. Key to our analysis is the use of `proxy controls': covariates that do not satisfy a standard `unconfoundedness'
Deaner, Ben
core
Determinants of interregional migration in Italy:A panel data analysis [PDF]
After two decades of low internal migration rates, official national statistics report a considerable increase of internal mobility which started in 1996 and still continues to grow at the time of writing.
Etzo, Ivan
core +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
In the literature, although there are studies examining the stock values by applying the ratio analysis method with the data obtained from the financial tables of football clubs, there are limited number of studies examining the factors affecting the ...
Hüseyin Enes Erkoçak, Mustafa Ay
doaj

