Results 121 to 130 of about 27,018,147 (310)

November Oversight Report [PDF]

open access: yes, 2009
November report of the U.S. Congressional Oversight Panel describing their activities and findings regarding the U.S. Treasury's Guarantee Program, including an overview of Guarantees in general, and the effectiveness and impacts of the Treasury's ...
United States. Congressional Oversight Panel.
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Semiparametric Trending Panel Data Models with Cross-Sectional Dependence [PDF]

open access: yes
A semiparametric fixed effects model is introduced to describe the nonlinear trending phenomenon in panel data analysis and it allows for the cross-sectional dependence in both the regressors and the residuals.
Jia Chen, Jiti Gao, Degui Li
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

SLOW MOVERS IN PANEL DATA

open access: yesEconometric Theory
Panel data often contain stayers and slow movers . The literature proposes an estimator for the average partial effects (APEs) for this setting without a formal theory. The literature is also silent about inference in the presence of stayers and many slow movers.
Sasaki, Yuya, Ura, Takuya
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

July Oversight Report

open access: yes, 2009
July report of the U.S. Congressional Oversight Panel describing their activities and findings regarding farm loan restructuring, including sections on agriculture markets, and farm credit ...
United States. Congressional Oversight Panel.
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

January Oversight Report

open access: yes, 2009
January report of the U.S. Congressional Oversight Panel describing their activities and findings regarding the U.S.
United States. Congressional Oversight Panel.
core   +1 more source

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