Results 111 to 120 of about 1,254,937 (311)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

ESTIMATION OF GEOGRAPHICALLY WEIGHTED PANEL REGRESSION MODEL WITH BISQUARE KERNEL WEIGHTING FUNCTION ON PERCENTAGE OF STUNTING TODDLERS IN INDONESIA

Barekeng
Stunting is a condition of failure to thrive in children under five years old due to chronic malnutrition. Efforts that can be made to reduce the incidence of stunting in Indonesia are to identify factors that are thought to affect the incidence of ...
Asnita Asnita, Sifriyani Sifriyani, Meirinda Fauziyah   +2 more
doaj   +1 more source

Epidemiology of Δ8THC-Related Carcinogenesis in USA: A Panel Regression and Causal Inferential Study. [PDF]

Int J Environ Res Public Health, 2022
Reece AS, Hulse GK.
europepmc   +1 more source

Works Councils and the Productivity Impact of Direct Employee Participation [PDF]

This paper measures the productivity impact of management-led participative establishment practices. On the basis of a representative German establishment data set, the IAB establishment panel, the study finds that the presence of team-work, a reduction ...
Zwick, Thomas
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Congenital anomaly epidemiological correlates of Δ8THC across USA 2003-16: panel regression and causal inferential study. [PDF]

Environ Epigenet, 2022
Reece AS, Hulse GK.
europepmc   +1 more source

On the Estimation of Panel Regression Models with Fixed Effects [PDF]

This paper considers estimation of panel data models with fixed effects. First, we will show that a consistent ``unrestricted fixed effects'' estimator does not exist for autoregressive panel data models with initial conditions.
Hugo Kruiniger
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Cannabinoid and substance relationships of European congenital anomaly patterns: a space-time panel regression and causal inferential study. [PDF]

Environ Epigenet, 2022
Reece AS, Hulse GK.
europepmc   +1 more source

A Test of Separability and Random Effects in Production Function with Decomposed IT Capital [PDF]

Separability Test, IT-using Effect, Panel ...
Ha, Bongchan, Pyo, Hak K.
core