Results 91 to 100 of about 454,560 (254)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Modelling climate variabilities and global rice production: A panel regression and time series analysis. [PDF]

open access: yesHeliyon, 2023
Joseph M   +5 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Mid-quantile regression for discrete panel data

open access: yesJournal of Statistical Computation and Simulation
We propose novel quantile regression methods when the response is discrete and the data come from a longitudinal design. The approach is based on conditional mid-quantiles, which have good theoretical properties even in the presence of ties. Optimization of a ridge-type penalized objective function accommodates for the data dependence.
Russo, Alfonso   +2 more
openaire   +6 more sources

Drivers of Carbon Emissions in China’s Construction Industry: A Perspective from Interregional Carbon Transfer

open access: yesBuildings
The construction sector is pivotal to China’s economy, with interregional trade driving carbon emission transfers. This study uses 2007–2017 panel data from 30 provinces to analyze provincial carbon transfer patterns, combining input-output analysis and ...
Wenwen Xiao   +3 more
doaj   +1 more source

A panel regression analysis for the COVID-19 epidemic in the United States. [PDF]

open access: yesPLoS One, 2022
Guo Y   +12 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

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