Results 71 to 80 of about 509,644 (312)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Panel smooth transition regression models [PDF]
, 2005 We develop a non-dynamic panel smooth transition regression model with fixed individual effects. The model is useful for describing heterogenous panels, with regression coefficients that vary across individuals and over time. Heterogeneity is allowed for by assuming that these coefficients are continuous functions of an observable variable through a ...
Andres Gonzalez +2 more
openaire +6 more sources
Does Financial Development Drive Entrepreneurship in Africa? A Panel Data Analysis
Managing Global TransitionsEntrepreneurship in Africa faces a multitude of challenges, with financial issues being prominently discussed in scholarly literature. Thus, this study explores how financial development plays a crucial role in encouraging entrepreneurship in Africa ...
Afees Oluwashina Noah +1 more
doaj +1 more source
Uluslararası Ekonomi, İşletme ve Politika Dergisi, 2018 Petrol fiyatları dünya ekonomisine yön verenekonomik göstergelerden birisidir. Petrol fiyatında meydana gelen değişimlerhem makroekonomik değişkenleri hem de hisse senedi piyasası değişkenlerinietkileyebilmektedir.
Aziza Syzdykova
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Study of State-Owned Enterprises (SOEs) Profitability in Indonesia 2012-2016 Period
Sriwijaya International Journal of Dynamic Economics and Business, 2020 One of the purposes of the establishment of SOEs is to become a source of funding for the state. But unfortunately, the losses and potential bankruptcy is still a business challenge to date.
Muhamad Fathul Muin +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Testing Panel Data Regression Models with Spatial Error Correlation [PDF]
This paper derives several Lagrange Multiplier tests for the panel data regression model with spatial error correlation. These tests draw upon two strands of earlier work.
Badi H. Baltagi +2 more
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source