Advanced Functional Materials, EarlyView.Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro +25 more
wiley +1 more source
The use of logic for machine learning models in sepsis. [PDF]
Intensive Care Med ExpLavage DR +5 more
europepmc +1 more source
Thermoresponsive Soft and Self‐Anchoring Cuff Electrode for Chronic Peripheral Interfaces
Advanced Functional Materials, EarlyView.A novel thermoresponsive, soft and self‐anchoring (TSSA) cuff electrode utilizing shape memory polymers achieves autonomous, sutureless peripheral nerve fixation. Driven by thermally induced pre‐strain and tissue adhesion, the device self‐closes and softens at body temperature, successfully minimizing mechanical mismatch. This adaptive platform ensures
Seungjun Lee +4 more
wiley +1 more source
Suprathreshold non-volatile flavour perception is associated with multiple species rather than any single species via bacterial metabolism. [PDF]
J Oral MicrobiolZhang S, Shoaie S, Carpenter GH.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Garbage in, garbage out: stringent quality control of behavioral data boosts signal in brain-behavior associations. [PDF]
Cereb CortexElsayed M +3 more
europepmc +1 more source
Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy
Advanced Healthcare Materials, EarlyView.This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato +8 more
wiley +1 more source
Correction: Effects of isometric training based on the entire population on blood pressure regulation: systematic review and meta-analysis of randomized controlled trials. [PDF]
Front Public HealthYan Y, Sun C, Pan L, Ma H, Xie H.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez +8 more
wiley +1 more source
PCR profiling of tumor-associated microorganisms in tissue of primary epithelial malignant tumors of colorectal origin: associations with key clinicopathological characteristics. [PDF]
Front Cell Infect MicrobiolShakhpazyan NK +7 more
europepmc +1 more source