Results 81 to 90 of about 3,959,626 (304)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

RE-EXAMINATION OF WAGNER’S LAW FOR OECD COUNTRIES [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2013
This paper investigates the relationship between government spending and economic growth. Economictheory generally expects a negative relationship between these variables for rich countries with large public sectors.However, empirical studies often ...
KORHAN GOKMENOGLU, VOLKAN ALPTEKIN
doaj  

The ASEAN experience of the purchasing power parity theory

open access: yesFinancial Innovation, 2018
We used panel data analysis to evaluate the relative purchasing power parity (PPP) hypothesis of the ten ASEAN member countries between 1973 and 2015.
S. M. Woahid Murad   +1 more
doaj   +1 more source

Panel unit root tests of purchasing power parity hypothesis: Evidence from Turkey [PDF]

open access: yes
In this paper, we employ some front page panel unit root tests to examine the validity of the purchasing power parity hypothesis in Turkey. Using monthly observations panel data of nine major county’s currency dates January 2003 through April 2010, we ...
Gozgor, Giray
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

TESTING MONETARY EXCHANGE RATE MODELS WITH PANEL COINTEGRATION TESTS [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2015
The monetary exchange rate models explain the long run behaviour of the nominal exchange rate. Their central assertion is that there is a long run equilibrium relationship between the nominal exchange rate and monetary macro-fundamentals.
Szabo Andrea
doaj  

Is there Really a Unit Root in the Inflation Rate? More Evidence from Panel Data Models [PDF]

open access: yes
Time series unit root evidence suggests that inflation is nonstationary. By contrast, when using more powerful panel unit root tests, Culver and Papell (1997) find that inflation is stationary.
Westerlund, Joakim, Basher, Syed A.
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Purchasing power parity revisited: a comprehensive panel study with structural breaks and common factors across 63 economies

open access: yesCogent Economics & Finance
We reassess the long-run validity of Purchasing Power Parity (PPP) using the PANIC–Fourier panel unit-root test that allows for smooth structural breaks and common factors, complemented by sharp breaks and common-factor panel tests, on monthly real ...
Jamal Husein   +3 more
doaj   +1 more source

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