Results 71 to 80 of about 1,556 (147)

Nanopore direct RNA sequencing and the epitranscriptome: Advances in mapping native RNA landscapes

iMeta, Volume 5, Issue 3, June 2026.
Nanopore direct RNA sequencing advances transcriptomics by capturing full‐length transcripts and multiple RNA modifications; this review details its principles, workflows, tools, applications, challenges, and future research potential. Abstract Nanopore direct RNA sequencing (DRS) has transformed transcriptomics by enabling single‐molecule, long‐read ...
Tianyuan Zhang, Jia Li, Chao Tang, You Wu, Hao Wu, Xi‐Tong Zhu, Ziyang Luo, Hang Qin, Lishan Ding, Yu Zeng, Shiou Yih Lee, Xiaotao Shen, Shiwen Gao, Zhaoyang Tian, Qian Tang, Mian Li, Muhammad Tahir Ul Qamar, Yang Dong, Komivi Dossa, Yaxuan Zhang, Hu Chen, Sanqi An, Xiang Yu, Lu Chen, Dingjie Wang, Shengli Li, Ling‐Ling Chen, Yanqiang Li   +27 more
wiley   +1 more source

Comparison of methods for building pangenome graphs

, 2022
Graph-based pangenomes could mitigate the bias from the use of a single reference genome. However, the impact of different pangenome integration approaches on the properties of the resulting graph remains unknown. In this study, we compared three methods for building pangenome graphs from multiple genome assemblies.
Crysnanto, Danang; id_orcid0000-0003-4444-9371, Leonard, Alexander; id_orcid0000-0001-8425-5630, Pausch, Hubert; id_orcid0000-0002-0501-6760   +2 more
openaire   +3 more sources

A Roadmap for Breeding Sweet Tomatoes

Modern Agriculture, Volume 4, Issue 1, June 2026.
This graphical abstract outlines four breeding strategies for enhancing sugar content and sweetness in tomato fruits: (1) Identification of key genes and functional variant loci regulating fruit sugar accumulation through systematic germplasm collection, genome‐wide association studies (GWAS), map‐based cloning, and reverse genetics approaches.
Jie Chen, Hongjun Lyu, Jinzhe Zhang
wiley   +1 more source

Investigating the topological motifs of inversions in pangenome graphs [PDF]

Recent technological advances have accelerated the production of high-quality genome assemblies within species, driving the growing use of pangenome graphs in genetic diversity analyses.
Lemaitre, Claire, Dubois, Siegfried, Romain, Sandra, Legeai, Fabrice   +3 more
core   +1 more source

vgteam/sv-genotyping-paper: Revised code repository for "Genotyping structural variants in pangenome graphs using the vg toolkit" [PDF]

, 2019
This repository contains the commands and scripts used for the revised version of our manuscript Genotyping structural variants in pangenome graphs using the vg toolkit ...
Glenn Hickey, Jean Monlong, David Heller
core   +1 more source

Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Wheat (Triticum aestivum L.), a foundation of global food security, faces persistent threats from stripe rust caused by Puccinia striiformis f. sp. tritici (Pst). The pathogen thrives in cool and humid environments and regularly causes epidemics that lead to severe yield losses.
Farkhandah Jan, Mukesh Rathore, Dinesh Kumar Saini, Ayushi Singh, Naeela Qureshi, Nikita Aggarwal, Mahpara Bashir, Mehnaz Shakeel, Vikas Gupta, Sundeep Kumar, Rajeev Kumar Varshney, Reyazul Rouf Mir   +11 more
wiley   +1 more source

Third Generation Genome Sequencing of the Endobacterium Corynebacterium kroppenstedtii subsp. demodicis Reveals Details of Its Microbe‐Host‐Interaction With the Most Complex Human Commensal, Demodex folliculorum

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
The symbiotic interaction between Demodex folliculorum and Corynebacterium kroppenstedtii subsp. demodicis. Created by the author based on genomic and functional analyses presented in this work. The tripartite interaction between the human host, the mite Demodex folliculorum, and its endosymbiont Corynebacterium kroppenstedtii subsp. demodicis.
T. Steegmüller, S. Walch, S. Gschwendtner, A. Klingl, L. E. French, M. Flaig, B. M. Clanner‐Engelshofen   +6 more
wiley   +1 more source

Integrative Advances in Equine Genomics From Reference Assemblies to Evolutionary History and Key Traits

Evolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Horses are major domestic animals and cultural symbols that have accompanied humans for millennia. They underpin transport, agriculture, warfare and sport, and also provide a model for studying domestication, complex traits and adaptive evolution.
Ying Lu, Ruoshan Ma, Bo Wang, Jiao Wu, Yuqing Chong, Zhendong Gao, Weidong Deng   +6 more
wiley   +1 more source

VERNALIZATION2 alters early tiller development in a facultative spring hexaploid bread wheat

New Phytologist, Volume 250, Issue 6, Page 4022-4035, June 2026.
Summary An extended period of cold exposure enables the process of vernalization in winter cereals and is important for the synchronised timing of the floral transition. The cereal‐specific floral repressor VERNALIZATION2 (VRN2) has an integral role in vernalization, yet this locus remains poorly characterised in facultative spring hexaploid wheat ...
Dominique Hirsz, Harry Taylor, India Lacey, Wenxue Wu, Adam Gauley, Laura Dixon   +5 more
wiley   +1 more source

Population genomics analyses on pangenome graphs

, 2020
Studies of genomes typically assume a single linear reference genome. This can make it difficult to observe sequences in other genomes that are divergent from the reference, which in turn can limit the accuracy and completeness of our analyses. To address this limitation, we can work with pangenome reference systems that represent the ...
Villani, Flavia, Porto, Francesco, Guarracino, Andrea, Williams, Robert W, Prins, Pjotr, Vedova, Gianluca Della, Garrison, Erik, Colonna, Vincenza   +7 more
openaire   +1 more source