Results 121 to 130 of about 105,530 (297)

Cytotoxic Activity of Opopanax hispidus (Friv.) Griseb.: Characterization of a New Chalcone‐type Compound

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The present study aimed to investigate cytotoxic compounds of Opopanax hispidus (Friv.) Griseb. through in vitro, in silico, and phytochemical analyses. The cytotoxic activity of O. hispidus was evaluated against four different cancer cell lines – lung (A549), breast (MCF‐7), liver (HepG2), and cervix (HeLa) – as well as one healthy cell line (
Kevser Taban   +7 more
wiley   +1 more source

Brain‐derived neurotrophic factor (BDNF) levels in panic disorder: A systematic review and meta‐analysis

open access: yesBrain and Behavior
Background The existing literature on the association between brain‐derived neurotrophic factor (BDNF) protein levels and panic disorder presents inconsistent findings. This systematic review and meta‐analysis aim to synthesize the available evidence and
Arman Shafiee   +3 more
doaj   +1 more source

Examining the Impact of Role Overload on Knowledge Hiding and Knowledge Manipulation

open access: yesCanadian Journal of Administrative Sciences / Revue Canadienne des Sciences de l'Administration, EarlyView.
ABSTRACT Role overload was rated as one of the top workplace stressors by the American Psychological Association in 2015. Drawing from the stressor‐emotion model of Counterproductive Work Behaviour, we examine the indirect effect of role overload on knowledge hiding and manipulation, via negative affect.
Jessica R. L. Good   +3 more
wiley   +1 more source

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan   +7 more
wiley   +1 more source

School spaces of dissensus: Protecting sexualities education in anti‐gender, anti‐Muslim and de‐democratising times

open access: yesThe Curriculum Journal, EarlyView.
Abstract This paper examines the intensified conflict over sexualities education curricula brought about by anti‐(trans)gender and anti‐Muslim policy and political discourse transnationally. Backlash against inclusive sexualities education has taken shape across several policy territories, driven in part by de‐democratising right‐wing populist ...
James Sutton   +2 more
wiley   +1 more source

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