Elevated Natural Killer Cell-Mediated Cytotoxicity Is Associated with Cavity Formation in Pulmonary Tuberculosis Patients [PDF]
Cavitation is a major pathological feature of pulmonary tuberculosis (TB). The study is aimed at investigating the mechanism of natural killer (NK) cells participating the cavity formation during Mycobacterium tuberculosis (MTB) infection.
Shanshan Li +9 more
doaj +3 more sources
The Panjian structure is an important longitudinal connecting member of Song Dynasty hall-type buildings in China. To study the lateral force resistance of such structures, a refined finite element model of Song-style hall-type single-room four-column ...
Yibin Chang, Jian Dai
doaj +4 more sources
Relevance of Intestinal Microbiota in Immunoglobulin A Vasculitis With Abdominal Involvement [PDF]
BackgroundWe explored the intestinal microbiota changes in IgAV with abdominal involvement (IgAV-GI) at the acute and convalescent stages and evaluated the role of intestinal microbiota in the clinical course of patients with IgAV.MethodsA total of 37 ...
Linqian Zhang +6 more
doaj +2 more sources
Blood vessel remodeling in late stage of vascular network reconstruction is essential for peripheral nerve regeneration [PDF]
One of the bottlenecks of advanced study on tissue engineering in regenerative medicine is rapid and functional vascularization. For a deeper comprehension of vascularization, the exhaustive, dynamic, and three‐dimensional depiction of perfused vascular ...
Gang Wang +7 more
doaj +2 more sources
Enhanced Serum IgG Detection Potential Using 38KD-MPT32-MPT64, CFP10-Mtb81-EspC Fusion Protein and Lipoarabinomannan (LAM) for Human Tuberculosis [PDF]
For the rapid, reliable, and cost-effective methods of tuberculosis (TB) auxiliary diagnosis, antibody (Ab) detection to multiple antigens of Mycobacterium tuberculosis (Mtb) has great potential; however, this methodology requires optimization.
Zhuohong Yan +8 more
doaj +2 more sources
Immunoassay with Novel Paired Antibodies for Detection of Lipoarabinomannan in the Pleural Fluid and Plasma of Patients with Tuberculous Pleurisy [PDF]
Tuberculous pleurisy (TP) is one of the most common forms of extrapulmonary tuberculosis, but its diagnosis is challenging. Lipoarabinomannan (LAM) antigen is a biomarker for Mycobacterium tuberculosis (Mtb) infection.
Zhuohong Yan +9 more
doaj +2 more sources
The balanced microenvironment regulated by the degradants of appropriate PLGA scaffolds and chitosan conduit promotes peripheral nerve regeneration [PDF]
Tissue-engineered nerve grafts (TENGs) are the most promising way for repairing long-distance peripheral nerve defects. Chitosan and poly (lactic-co-glycolic acid) (PLGA) scaffolds are considered as the promising materials in the pharmaceutical and ...
Panjian Lu +8 more
doaj +2 more sources
Association between response to anti-PD-1 treatment and blood soluble PD-L1 and IL-8 changes in patients with NSCLC [PDF]
In this study, we explored the dynamic changes in blood sPD-L1 and its clinical value during anti-PD-1 immunotherapy in non-small cell lung cancer (NSCLC) patients.
Ling Yi +8 more
doaj +2 more sources
The heterozygous mutation COL4A4 c.817-1G>A causes Alport syndrome in a Chinese family: a case report [PDF]
BackgroundAlport syndrome is an inherited glomerular disease that leads to progressive kidney failure, hearing loss, and eye problems. Diagnosis mostly relies on tests of tissue pathology and genetic analysis.
Dayan Wang +11 more
doaj +2 more sources
Integrated Analysis of Gut Microbiota and Metabolites in a Rat Necrotizing Enterocolitis Model [PDF]
Background/Aims: Necrotizing enterocolitis (NEC) is a critical gastrointestinal emergency in newborns, characterized by mucosal damage, gut microbial dysbiosis, and inflammation. This study aimed to identify differential gut microbiota and metabolites in
Panjian Lai, Dayan Wang, Xiaobing Li
doaj +2 more sources

