Enhanced Serum IgG Detection Potential Using 38KD-MPT32-MPT64, CFP10-Mtb81-EspC Fusion Protein and Lipoarabinomannan (LAM) for Human Tuberculosis [PDF]
Pathogens, 2022 For the rapid, reliable, and cost-effective methods of tuberculosis (TB) auxiliary diagnosis, antibody (Ab) detection to multiple antigens of Mycobacterium tuberculosis (Mtb) has great potential; however, this methodology requires optimization.
Zhuohong Yan +8 more
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The balanced microenvironment regulated by the degradants of appropriate PLGA scaffolds and chitosan conduit promotes peripheral nerve regeneration [PDF]
Materials Today Bio, 2021 Tissue-engineered nerve grafts (TENGs) are the most promising way for repairing long-distance peripheral nerve defects. Chitosan and poly (lactic-co-glycolic acid) (PLGA) scaffolds are considered as the promising materials in the pharmaceutical and ...
Panjian Lu +8 more
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Integrated Analysis of Gut Microbiota and Metabolites in a Rat Necrotizing Enterocolitis Model [PDF]
The Turkish Journal of GastroenterologyBackground/Aims: Necrotizing enterocolitis (NEC) is a critical gastrointestinal emergency in newborns, characterized by mucosal damage, gut microbial dysbiosis, and inflammation. This study aimed to identify differential gut microbiota and metabolites in
Panjian Lai, Dayan Wang, Xiaobing Li
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Association between response to anti-PD-1 treatment and blood soluble PD-L1 and IL-8 changes in patients with NSCLC [PDF]
Discover Oncology, 2023 In this study, we explored the dynamic changes in blood sPD-L1 and its clinical value during anti-PD-1 immunotherapy in non-small cell lung cancer (NSCLC) patients.
Ling Yi +8 more
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Soluble programmed cell death-ligand 1 as a new potential biomarker associated with acute coronary syndrome [PDF]
Frontiers in Cardiovascular Medicine, 2022 BackgroundSoluble programmed cell death-ligand 1 (sPD-L1) has been well documented to activate immunosuppression and is considered an essential predictor of negative clinical outcomes for several malignances and inflammatory conditions.
Shuping Li +13 more
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Mechanisms of action of bile acids in pediatric gastroesophageal reflux: Exploration through non-targeted and targeted metabolomics methods. [PDF]
PLoS ONEPurposeTo investigate the pathogenesis of pediatric bile reflux gastritis (BRG) using non-targeted and targeted metabolomics analyses of the changes and content differences of bile acids (BAs) in gastric juice.MethodsData from 25 pediatric BRG patients ...
Linqian Zhang +6 more
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Remote Sensing, 2022 This paper aims to study the application of hyperspectral technology in the classification of deep-sea manganese nodules. Considering the spectral spatial variation of hyperspectral images, the difficulty of label acquisition, and the inability to ...
Panjian Ye +5 more
doaj +3 more sources
Mechanisms underlying the cell-matrixed nerve grafts repairing peripheral nerve defects [PDF]
Bioactive MaterialsDecellularized extracellular matrix (dECM), with its distinct biological properties, has gained significant attention as a natural biomaterial. Leveraging its potentials, we successfully developed a three-dimensional matrix-based oriented nerve graft by ...
Shanshan Wang +5 more
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Epigenetic regulators combined with tumour immunotherapy: current status and perspectives [PDF]
Clinical EpigeneticsImmunotherapy, particularly immune checkpoint inhibitor therapy, has demonstrated clinical benefits in solid tumours. Despite its satisfactory clinical efficacy, it still faces several issues, such as limited eligibility, low response rates and ...
Huan Zhang +6 more
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Construction of Dual-Biofunctionalized Chitosan/Collagen Scaffolds for Simultaneous Neovascularization and Nerve Regeneration [PDF]
Research, 2020 Biofunctionalization of artificial nerve implants by incorporation of specific bioactive factors has greatly enhanced the success of grafting procedures for peripheral nerve regeneration.
Guicai Li +10 more
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