Parameter analysis on longitudinal lateral force resistance of Song dynasty timber frame with Panjian [PDF]
The Panjian structure is an important longitudinal connecting member of Song Dynasty hall-type buildings in China. To study the lateral force resistance of such structures, a refined finite element model of Song-style hall-type single-room four-column space timber frame containing Panjian structure was established based on the official building code ...
Yibin Chang, Jian Dai
doaj +12 more sources
Elevated Natural Killer Cell-Mediated Cytotoxicity Is Associated with Cavity Formation in Pulmonary Tuberculosis Patients [PDF]
Cavitation is a major pathological feature of pulmonary tuberculosis (TB). The study is aimed at investigating the mechanism of natural killer (NK) cells participating the cavity formation during Mycobacterium tuberculosis (MTB) infection.
Shanshan Li +9 more
doaj +3 more sources
The heterozygous mutation COL4A4 c.817-1G>A causes Alport syndrome in a Chinese family: a case report [PDF]
BackgroundAlport syndrome is an inherited glomerular disease that leads to progressive kidney failure, hearing loss, and eye problems. Diagnosis mostly relies on tests of tissue pathology and genetic analysis.
Dayan Wang +11 more
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Relevance of Intestinal Microbiota in Immunoglobulin A Vasculitis With Abdominal Involvement [PDF]
BackgroundWe explored the intestinal microbiota changes in IgAV with abdominal involvement (IgAV-GI) at the acute and convalescent stages and evaluated the role of intestinal microbiota in the clinical course of patients with IgAV.MethodsA total of 37 ...
Linqian Zhang +6 more
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Immunoassay with Novel Paired Antibodies for Detection of Lipoarabinomannan in the Pleural Fluid and Plasma of Patients with Tuberculous Pleurisy [PDF]
Tuberculous pleurisy (TP) is one of the most common forms of extrapulmonary tuberculosis, but its diagnosis is challenging. Lipoarabinomannan (LAM) antigen is a biomarker for Mycobacterium tuberculosis (Mtb) infection.
Zhuohong Yan +9 more
doaj +3 more sources
SARS-CoV-2 Infection Alters the Immune Microenvironment in Lung Cancer Patients Undergoing Immunotherapy and Affects Treatment Outcomes [PDF]
Background: The COVID-19 pandemic prompted investigation into the interaction between SARS-CoV-2 infection and immune checkpoint inhibitor (ICI) therapy in lung cancer patients. Understanding this interplay is crucial for optimizing cancer immunotherapy.
Yanjing Peng +5 more
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Berberine attenuates TNBS-induced colitis in mice by improving the intestinal microbiota [PDF]
ObjectiveTo investigate the effects of berberine (BBR) as a treatment on intestinal microecological alterations and enteritis in mice produced by TNBS.MethodsThere were seven mice per group: seven in the healthy group (Ctrl), seven in the TNBS-induced ...
Chao Li +13 more
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Establishment of novel anti-TIM-3 antibodies interfering with its binding to ligands [PDF]
The T cell immunoglobulin and mucin-domain containing-3 (TIM-3) receptor has gained significant attention as a promising target for cancer immunotherapy.
Zhuohong Yan +6 more
doaj +3 more sources
Preparation of Two Types p53 Recombinant Adenovirus and Quantitative Exogenous Expression of Green Fluorescence Protein by Flow Cytometry [PDF]
Background and objective The p53 as a transcription factor in cell stress was activated to regulate cell cycle and programmed cell death to inhibit tumor growth. Usually, p53 is kept in non-activated state through various mechanisms, including the action
Panjian WEI +6 more
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Blood vessel remodeling in late stage of vascular network reconstruction is essential for peripheral nerve regeneration [PDF]
One of the bottlenecks of advanced study on tissue engineering in regenerative medicine is rapid and functional vascularization. For a deeper comprehension of vascularization, the exhaustive, dynamic, and three‐dimensional depiction of perfused vascular ...
Gang Wang +7 more
doaj +2 more sources

