SARS-CoV-2 Infection Alters the Immune Microenvironment in Lung Cancer Patients Undergoing Immunotherapy and Affects Treatment Outcomes [PDF]
VirusesBackground: The COVID-19 pandemic prompted investigation into the interaction between SARS-CoV-2 infection and immune checkpoint inhibitor (ICI) therapy in lung cancer patients. Understanding this interplay is crucial for optimizing cancer immunotherapy.
Yanjing Peng +5 more
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Berberine attenuates TNBS-induced colitis in mice by improving the intestinal microbiota [PDF]
Frontiers in MicrobiologyObjectiveTo investigate the effects of berberine (BBR) as a treatment on intestinal microecological alterations and enteritis in mice produced by TNBS.MethodsThere were seven mice per group: seven in the healthy group (Ctrl), seven in the TNBS-induced ...
Chao Li +13 more
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Establishment of novel anti-TIM-3 antibodies interfering with its binding to ligands [PDF]
HeliyonThe T cell immunoglobulin and mucin-domain containing-3 (TIM-3) receptor has gained significant attention as a promising target for cancer immunotherapy.
Zhuohong Yan +6 more
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Preparation of Two Types p53 Recombinant Adenovirus and Quantitative Exogenous Expression of Green Fluorescence Protein by Flow Cytometry [PDF]
Chinese Journal of Lung Cancer, 2010 Background and objective The p53 as a transcription factor in cell stress was activated to regulate cell cycle and programmed cell death to inhibit tumor growth. Usually, p53 is kept in non-activated state through various mechanisms, including the action
Panjian WEI +6 more
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Soluble programmed cell death-ligand 1 as a new potential biomarker associated with acute coronary syndrome [PDF]
Frontiers in Cardiovascular Medicine, 2022 BackgroundSoluble programmed cell death-ligand 1 (sPD-L1) has been well documented to activate immunosuppression and is considered an essential predictor of negative clinical outcomes for several malignances and inflammatory conditions.
Shuping Li +13 more
doaj +2 more sources
Mechanisms underlying the cell-matrixed nerve grafts repairing peripheral nerve defects [PDF]
Bioactive MaterialsDecellularized extracellular matrix (dECM), with its distinct biological properties, has gained significant attention as a natural biomaterial. Leveraging its potentials, we successfully developed a three-dimensional matrix-based oriented nerve graft by ...
Shanshan Wang +5 more
doaj +2 more sources
Remote Sensing, 2022 This paper aims to study the application of hyperspectral technology in the classification of deep-sea manganese nodules. Considering the spectral spatial variation of hyperspectral images, the difficulty of label acquisition, and the inability to ...
Panjian Ye +5 more
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Epigenetic regulators combined with tumour immunotherapy: current status and perspectives [PDF]
Clinical EpigeneticsImmunotherapy, particularly immune checkpoint inhibitor therapy, has demonstrated clinical benefits in solid tumours. Despite its satisfactory clinical efficacy, it still faces several issues, such as limited eligibility, low response rates and ...
Huan Zhang +6 more
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Construction of Dual-Biofunctionalized Chitosan/Collagen Scaffolds for Simultaneous Neovascularization and Nerve Regeneration [PDF]
Research, 2020 Biofunctionalization of artificial nerve implants by incorporation of specific bioactive factors has greatly enhanced the success of grafting procedures for peripheral nerve regeneration.
Guicai Li +10 more
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PU SAPI DAN LEMBU AGRA: KAJIAN ANTROPONIMI BERDASARKAN ISI PRASASTI JAWA KUNO (ABAD KE-9–16 M) [PDF]
, 2021 Javanese literary works, especially the Panji tales, often feature human characters with animal names, such as Kuda Narawangsa, Kebo Kanigara, and Kidangwalangka. This naming phenomenon can also be found in old Javanese inscriptions.
Susanti, Ninie, Tri Sasongko, Chacuk
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