Results 51 to 60 of about 4,056 (179)

Ranibizumab with luseogliflozin in type 2 diabetes with diabetic macular oedema: A randomised clinical trial

Diabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2473-2484, May 2025.
Abstract Aims Anti‐vascular endothelial growth factor (VEGF) therapy is the standard treatment for diabetic macular oedema (DMO); however, unmet needs remain. This study aimed to assess the effectiveness of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in treating DMO.
Ryoichi Ishibashi, Yoko Takatsuna, Masaya Koshizaka, Tomoaki Tatsumi, Sho Takahashi, Kengo Nagashima, Ko Ishikawa, Tomomi Kaiho, Noriko Asaumi, Takayuki Baba, Shuichi Yamamoto, Koutaro Yokote, The COMET Trial investigators   +12 more
wiley   +1 more source

Anti-VEGF drugs compared with laser photocoagulation for the treatment of proliferative diabetic retinopathy: a systematic review and individual participant data meta-analysis

Health Technology Assessment
Background Proliferative diabetic retinopathy is a major cause of sight loss in people with diabetes, with a high risk of vitreous haemorrhage, tractional retinal detachment and other complications.
Mark Simmonds, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Matthew Walton, Rob Hodgson, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, João Pereira Figueira, Sobha Sivaprasad, John G Lawrenson, Tunde Peto, David Steel   +14 more
doaj   +1 more source

A novel navigated laser system brings new efficacy to the treatment of retinovascular disorders

Oman Journal of Ophthalmology, 2013
The laser photocoagulation is now treatment of choice for various retinovascular disorders. Conventional slit-lamp based laser delivery systems have many limitations including, questionable accuracy, need of contact lens with local anesthesia, and ...
Jay Chhablani, Igor Kozak, Giulio Barteselli, Sharif El-Emam   +3 more
doaj   +1 more source

Obesity, Metabolic Health, and Diabetic Complications in People With Type 1 Diabetes

Endocrinology, Diabetes &Metabolism, Volume 8, Issue 1, January 2025.
Obesity, metabolic health, and the development of diabetic complications in type 1 diabetes. ABSTRACT Aim The concept of metabolically healthy obesity (MHO) has not been studied in type 1 diabetes (T1D). By analysing datasets from the DCCT/EDIC study, we compared the development of diabetic complications by obesity and metabolic health over 30 years of
Yuanjie Mao, Jen‐Tzer Gau, Ning Jiang
wiley   +1 more source

Anti-VEGF drugs compared with laser photocoagulation for the treatment of diabetic retinopathy: a systematic review and meta-analysis

Health Technology Assessment
Background Diabetic retinopathy is a major cause of sight loss in people with diabetes. The most severe form, proliferative diabetic retinopathy, carries a high risk of vision loss, vitreous haemorrhage, macular oedema and other harms.
Mark Simmonds, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Matthew Walton, Rob Hodgson, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, John G Lawrenson, Tunde Peto, David Steel   +12 more
doaj   +1 more source

Combined Cytomegalovirus Retinitis and Vitreous Hemorrhage in an Immunocompromised Patient

Case Reports in Ophthalmological Medicine, Volume 2025, Issue 1, 2025.
Purpose: This study is aimed at describing a case of combined CMV retinitis and vitreous hemorrhage in an immunocompromised patient. Observations: A 38‐year‐old male who is known to have HIV presented to our emergency department complaining of decreasing vision in his left eye.
Abdulrahman Y. Alhoumaily, Abdulsalam M. Dheyab, Kamal Kishore   +2 more
wiley   +1 more source

Bilateral methamphetamine-induced ischemic retinopathy

American Journal of Ophthalmology Case Reports, 2019
Purpose: To describe the multimodal imaging and treatment of a 37-year-old male presenting with bilateral ischemic retinopathy induced by methamphetamine abuse.
Jingli Guo, Wenyi Tang, Wei Liu, Yongjin Zhang, Ling Wang, Wenji Wang   +5 more
doaj   +1 more source

Correlation Between Postoperative Vitreous Hemorrhage and Preoperative Evaluation of Optical Coherence Tomography Angiography in Proliferative Diabetic Retinopathy Surgery

Journal of Ophthalmology, Volume 2025, Issue 1, 2025.
Purpose: To measure and compare the extent of retinal neovascularization using optical coherence tomography angiography (OCTA) between patients with good postoperative outcomes for proliferative diabetic retinopathy (PDR) requiring surgical treatment and patients with vitreous hemorrhage (VH).
Yusuke Haruna, Mizuki Tagami, Gen Kinari, Atsushi Sakai, Shigeru Honda, Enrico Peiretti   +5 more
wiley   +1 more source

Individualised screening for diabetic retinopathy with proliferative retinopathy and macular oedema as separate end points

Acta Ophthalmologica, Volume 102, Issue 6, Page 627-634, September 2024.
Abstract Purpose A number of algorithms have been developed to calculate screening intervals for diabetic retinopathy on the basis of individual risk factors. However, these approaches have not considered proliferative diabetic retinopathy (PDR) and diabetic macular oedema (DME) as separate end points and death as competing risk.
Toke Bek, Nis Andersen, Jens Andresen, Jakob Grauslund, Javad Hajari, Caroline Schmidt Laugesen, Katja Schielke, Line Petersen   +7 more
wiley   +1 more source

Microaneurysm detection using high‐speed megahertz optical coherence tomography angiography in advanced diabetic retinopathy

Acta Ophthalmologica, Volume 102, Issue 5, Page e687-e695, August 2024.
Abstract Purpose To compare detection rates of microaneurysms (MAs) on high‐speed megahertz optical coherence tomography angiography (MHz‐OCTA), fluorescein angiography (FA) and colour fundus photography (CF) in patients with diabetic retinopathy (DR).
Kim Lien Huber, Heiko Stino, Thomas Schlegl, Irene Steiner, Gergely Nagy, Michael Niederleithner, Bernhard Baumann, Wolfgang Drexler, Rainer A. Leitgeb, Ursula Schmidt‐Erfurth, Tilman Schmoll, Andreas Pollreisz   +11 more
wiley   +1 more source