Results 101 to 110 of about 22,431 (234)

OMICS Profiling Identifies Signatures of Senescence in Osteogenesis Imperfecta Osteoblasts Counteracted by 4-PBA. [PDF]

J Cell Mol Med
Besio R, Maffioli E, Palladino E, Sala A, Garibaldi N, Izzi V, Forlino A, Tedeschi G.   +7 more
europepmc   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

PANTHER Score: Protein-Affinity for Nucleic Target-binding, Hybridization, and Energy Regression. [PDF]

RNA
Aletayeb P, Biswas AD, Rocca S, Talarico C, Vistoli G, Pedretti A.   +5 more
europepmc   +1 more source

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber, Federico M. Gasparoli, Ziqin Yang, Nicole A. Teaney, Rachel Hobson, Lahin Lalani, Gayathri Srinivasan, Dosh Whye, Ranit Karmakar, Elizabeth D. Buttermore, Kellen D. Winden, Cidi Chen, Mustafa Sahin   +12 more
wiley   +1 more source

OrthoGrafter: Rapid Identification of Orthologs from Precomputed Placement in Phylogenetic Trees. [PDF]

J Mol Evol
Williams CM, Thomas PD.
europepmc   +1 more source

Local Knowledge and Human–Wildlife Conflict in the Conservation of the Harpy Eagle (Harpia harpyja) in Its Main Refuge in the Atlantic Forest

Ecology and Evolution, Volume 16, Issue 5, May 2026.
The Harpy Eagle (Harpia harpyja), a top predator of Neotropical forests, faces severe threats across its range, including in the Atlantic Forest. Using 50 years of occurrence records, including nests and multiple age classes, we document the species' persistence in one of its last reproductive refuges while revealing ongoing human–wildlife conflicts ...
Brener Fabres, Tânia Margarete Sanaiotti, Gustavo Magnago, Gabriel Scaldaferro Bonfa, Henrique Mariano, Paulo Quadros de Menezes, José Alves da Costa Filho, Mylena Kaizer, Carlos Hartur Ribeiro Nóia, Frederico Pereira de Castro Andrade, Francisca Helena Aguiar‐Silva, Olivier Jaudoin, Ana Carolina Srbek‐Araujo, Geovane Souza Siqueira, Aureo Banhos   +14 more
wiley   +1 more source

PANTHER: Prasugrel-based aneurysm treatment with non-identical telescoping with flow diversion with hydrophilic polymer coating for endovascular reconstruction in acute subarachnoid hemorrhage. [PDF]

Interv Neuroradiol
Khanafer A, Hajiyev K, von Gottberg P, Almohammad M, Aburub A, Forsting M, Ganslandt O, Henkes H.   +7 more
europepmc   +1 more source

Evolution of Resistance to Avian Malaria Infection in an Endemic Hawaiian Honeycreeper

Ecology and Evolution, Volume 16, Issue 5, May 2026.
Hawaiian honeycreepers, a group of endemic song birds, represent one of the most stunning examples of an adaptive radiation. An evolutionary history devoid of malaria‐causing parasites has made them incredibly susceptible to disease. This work sought to identify genomic correlates of avian malaria infection.
John H. Neddermeyer, Loren Cassin‐Sackett, Eben H. Paxton, Michael G. Campana, Robert C. Fleischer, Jeffrey T. Foster   +5 more
wiley   +1 more source

From Triplex to Quadruplex: Enhancing CDC's Respiratory qPCR Assay with RSV Detection on Panther Fusion^® Open Access™. [PDF]

Microorganisms
Caballero Méndez A, Sosa Ortiz MN, Reynoso de la Rosa RA, Abreu Bencosme ME, Montero Lebrón KV.   +4 more
europepmc   +1 more source

No Evidence of Reactive Avoidance of Baboons (Papio ursinus and Papio anubis) to the Presence of Predators

Ecology and Evolution, Volume 16, Issue 5, May 2026.
In this study, we took advantage of the largest camera trap‐based monitoring project in Africa, Snapshot Safari and analyzed 10,000 camera trap detections from three sites in South Africa and one site in Tanzania to test whether baboons exhibit species‐specific reactive avoidance in response to the presence of predators. ABSTRACT Predators exert strong
N. van Rooyen, L. Thel, J. A. Venter, H. Fritz, F. Prugnolle, V. Rougeron   +5 more
wiley   +1 more source