Results 91 to 100 of about 163 (149)

Pegargiminase Suppresses the Fanconi Anemia Pathway and Promotes Melphalan‐Induced DNA Double‐Strand Breaks in Uveal Melanoma

open access: yesPigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.
ADI‐PEG20 enhances melphalan‐induced DNA DSBs in UM cells. We describe potentiation of DNA DSBs in UM cell lines upon treatment with ADI‐PEG20 and melphalan (92.1 cells with STRIDE by intoDNA). ADI‐PEG20 suppresses multiple members of the FA pathway—a known resistance mechanism for melphalan—providing a rationale for exploring this drug combination in ...
Iuliia Pavlyk   +10 more
wiley   +1 more source

The Intricate Mechanism of Nitric Oxide Synthase

open access: yesJournal of Computational Chemistry, Volume 47, Issue 17, 30 June 2026.
The mechanism for NO formation by Nitric Oxide Synthase (NOS) has been studied using accurate DFT methods. A long‐range electron transfer from the cofactor H4B leads to formation of H2O2. ABSTRACT The biological formation of NO is performed by nitric oxide synthase.
Per E. M. Siegbahn
wiley   +1 more source

Jaguar attack on a child: case report and literature review. [PDF]

open access: yesWest J Emerg Med, 2015
Iserson KV, Francis AM.
europepmc   +1 more source

Exercise Training Stimulates the Release of Glutathione Peroxidase 1 (GPX1)‐Enriched Extracellular Vesicles That Promote Angiogenesis

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Exercise Training Stimulates the Release of Glutathione Peroxidase 1 (GPX1)‐Enriched Extracellular Vesicles that Promote Angiogenesis. The results from this study suggest that EVs isolated from blood immediately after the last bout of endurance exercise training (ExerV) are enriched in antioxidants. ExerVs stimulate vascular growth both in vitro and in 
Alexander M. Fliflet   +23 more
wiley   +1 more source

Molecular and serological survey of carnivore pathogens in free-roaming domestic cats of rural communities in southern Chile. [PDF]

open access: yesJ Vet Med Sci, 2019
Sacristán I   +12 more
europepmc   +1 more source

Risk and Prognosis of Hamstring Injuries in the National Football League: A 12-Year Review. [PDF]

open access: yesOrthop J Sports Med
Jenkins R   +6 more
europepmc   +1 more source

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