Results 11 to 20 of about 4,774 (150)

Panton-Valentine Leukocidin–Positive MRSA, Shanghai

Emerging Infectious Diseases, 2010
To the Editor: The development of methicillin resistance in community strains of Staphylococcus aureus is a notable step in the evolution of this pathogen. Unlike their equivalents in the hospital environment, community-associated methicillin-resistant S.
Li-Zhong Han, Pak-Leung Ho, Yu-Xing Ni, Hong Zhang, Yan-Qun Jiang, Hai-Qing Chu, Yang Sun, Yi-Bo Zhang   +7 more
doaj   +3 more sources

Panton-Valentine Leukocidin–producing Staphylococcus aureus

Emerging Infectious Diseases, 2006
To the Editor: Panton-Valentine leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus that causes leukocyte destruction and tissue necrosis (1). Although produced by
Amos Adler, Violeta Temper, Colin S. Block, Nitsa Abramson, Allon E. Moses   +4 more
doaj   +3 more sources

Panton-Valentine Leukocidin Genes in Staphylococcus aureus

Emerging Infectious Diseases, 2006
The pathogenicity of Staphylococcus aureus depends on various bacterial surface components and extracellular proteins. However, the precise role of single virulence determinants in relation to infection is hard to establish. The frequent recovery of staphylococcal isolates that produce leukocidal toxins from patients with deep skin and soft tissue ...
Damian C. Melles, Willem B. van Leeuwen, Hélène A.M. Boelens, Justine K. Peeters, Henri A. Verbrugh, Alex van Belkum   +5 more
doaj   +4 more sources

Panton-Valentine Leukocidin in Necrotizing Pneumonia: A Case Report. [PDF]

Cureus
Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus (S. aureus) is a rare but clinically significant cause of community-acquired pneumonia (CAP). This toxin leads to extensive tissue destruction and severe inflammation, often progressing to necrotizing pneumonia, septic shock, and multiorgan failure, representing a challenge in medical ...
Costa CA, Inácio H, Trevas S, Simas Â.
europepmc   +3 more sources

Panton-Valentine Leukocidin–positive Staphylococcus aureus, Singapore

Emerging Infectious Diseases, 2004
To the Editor: Necrotizing community-acquired pneumonia attributable to Panton-Valentine leukocidin–producing strains of Staphylococcus aureus has been described as a distinct clinical syndrome with a high death rate in young, immunocompetent patients (1,2). This letter details the first reported case of necrotizing pneumonia caused by Panton-Valentine
Li-Yang Hsu, Tse-Hsien Koh, Devanand Anantham, Asok Kurup, Kenneth Ping Wah Chan, Ban-Hock Tan   +5 more
doaj   +2 more sources

Exploration of compounds to inhibit the Panton-Valentine leukocidin of Staphylococcus aureus. [PDF]

Med Microbiol Immunol
AbstractThe Panton-Valentine leukocidin (PVL) of Staphylococcus aureus is associated with necrotizing infections. After binding to complement 5a receptor (C5aR/CD88) and CD45 it causes cytolysis in polymorphonuclear neutrophils (PMNs) as well as inflammasome activation in monocytes.
Grebe T, Sarkari MT, Cherkaoui A, Schaumburg F.   +3 more
europepmc   +3 more sources

A Rare Case of Panton-Valentine Leukocidin-Related Cervical Empyema. [PDF]

Asian J Neurosurg, 2023
Abstract Staphylococcus aureus is found in the normal skin and mucosa of approximately 30% of healthy populations and is the most common pathogen in human disease associated with bacteria. They are divided into methicillin-sensitive S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA). The S.
Le H, Nguyen DLT, Ton MNT, Phan D, Tran AHN, Truong VT.   +5 more
europepmc   +3 more sources

Panton-Valentine leukocidin osteomyelitis in children: a growing threat [PDF]

British Journal of Hospital Medicine, 2015
Panton-Valentine leukocidin-producing Staphylococcus aureus osteomyelitis is associated with multiple complications including multiple abscesses, deep vein thrombosis and fulminant sepsis. This article reviews the literature concerning this emerging threat which is currently under-recognized.
Sheikh, HQ, Aqil, A, Kirby, A, Hossain, FS   +3 more
openaire   +3 more sources

Outbreak of Panton-Valentine Leukocidin–Associated Methicillin-Susceptible Staphylococcus aureus Infection in a Rugby Team, France, 2010–2011

Emerging Infectious Diseases, 2016
Staphylococcus aureus strains that produce Panton-Valentine leukocidin are known to cause community infections. We describe an outbreak of skin abscesses caused by Panton-Valentine leukocidin–producing methicillin-susceptible S.
Elodie Couvé-Deacon, Anne Tristan, Nathalie Pestourie, Christian Faure, Valérie Doffoel-Hantz, Fabien Garnier, Frédéric Laurent, Gerard Lina, Marie-Cecile Ploy   +8 more
doaj   +1 more source

TPST2-mediated receptor tyrosine sulfation enhances leukocidin cytotoxicity and S. aureus infection

Frontiers in Immunology, 2023
BackgroundAn essential fact underlying the severity of Staphylococcus aureus (S. aureus) infection is the bicomponent leukocidins released by the pathogen to target and lyse host phagocytes through specific binding cell membrane receptors.
Jie He, Xianggui Yang, Kai Yang, Honglin Xu, Cheng Chen, Junxiong Wang, Jun Zeng   +6 more
doaj   +1 more source