Case Report: Pancreatic Paraganglioma Mimicking a Well‐Differentiated Neuroendocrine Tumor: The Importance of Cytokeratin Immunohistochemistry [PDF]
ABSTRACT Paragangliomas (PGLs) are uncommon neuroendocrine tumors most commonly found in the head and neck that originate from neural crest cells. Primary pancreatic paraganglioma is exceedingly rare and has largely been described in case reports and small case series. We present the case of a 79‐year‐old woman with an incidental pancreatic head lesion
Tanner Storozuk, Marc Vecchio
wiley +2 more sources
Interobserver variation among cytopathologists in the evaluation of oncocytic cell‐predominant thyroid FNA cytology: A validation study of 173 cases with surgical follow‐up and correlation with molecular testing [PDF]
Abstract Background Interpretation of oncocytic cell‐predominant cytologies (OCP) is very challenging as a majority of those cases are diagnosed as indeterminate, including atypia of undetermined significance (AUS) and follicular neoplasm (FN). The authors previously reported a combination of a four‐risk factor model highly predictive of neoplasia and ...
Tarik M. Elsheikh +5 more
wiley +2 more sources
A Unified Deep Learning Framework for Instance Segmentation Across Diverse Cytological Stains [PDF]
Transformer‐based unified cytology segmentation across Papanicolaou, Feulgen and AgNOR achieves stain‐invariant performance. Mask2Former maximises boundary precision (AP75) on the combined dataset, enabling one model to replace multiple stain‐specific deployments without accuracy loss while simplifying clinical integration.
Luís Otávio Santos +6 more
wiley +2 more sources
The current status of the Papanicolaou smear [PDF]
Since its introduction as a screen for cervical cancer in the late 1940s, the Pap smear has become one of the most widely accepted screening procedures for cancer. Numerous scientific studies have now attested to its effectiveness. However, important issues related to the Pap smear, including cytologic nomenclature, accuracy, regulatory procedures, and
Robert Smith, H M Shingleton
exaly +3 more sources
Cytopathology Terminology Systems: European Federation of Cytological Societies Survey on Practice in Europe [PDF]
Cytology terminologies are widely accepted within Europe based on EFCS survey. The Bethesda System for reporting cervical cytology and the Bethesda System for reporting thyroid cytopathology have been implemented by most of the responding countries. ABSTRACT Cytopathologists communicate with clinicians via cytopathology reports.
Ivana Kholová +46 more
wiley +2 more sources
Attitudes to Papanicolaou smears
Preventive health behavior has been defined as behavior aimed at the prevention or detection of disease in an asymptomatic state. When cervical cancer is discovered and treated in the premalignant stage, the cure rate is 95% or higher. The success of the screening program for cervical cancer depends at least partially on women's acceptance of and ...
exaly +3 more sources
Adjusted Risk Stratification of Indeterminate Thyroid Nodules Using the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI‐RADS) [PDF]
ABSTRACT Background The TI‐RADS guides the initial management of thyroid nodules, but the malignancy risk across different categories of cytologically indeterminate thyroid nodules (CITNs), particularly AUS and FN, remains unclear. Methods We reviewed thyroid FNA specimens diagnosed as AUS or FN with TI‐RADS scores of 3, 4, or 5 from 2017 to 2025 ...
Jessica Zhao +8 more
wiley +2 more sources
The Diagnostic Value of Immunohistochemistry and Biomarkers in the Diagnosis of Mesothelioma in Pleural/Peritoneal Effusions [PDF]
ABSTRACT Background Mesothelioma is a rare tumor that arises from the serosal cells lining the serous cavities, most commonly the pleura followed by the peritoneum. Presenting symptoms include pleuritic pain and bloody effusions that recur. Although cytologic analysis cannot determine the mesothelial subtype or in situ from invasive disease, the ...
Suzanne M. Selvaggi
wiley +2 more sources
Objectives:Klebsiella pneumoniae carbapenemase (KPC)–producing K. pneumoniae (KPC-Kp) emerge as a major healthcare concern worldwide. Despite the significance of infections before and after allogeneic hematopoietic cell transplantation (alloHCT), the ...
Eleni Gavriilaki +13 more
doaj +1 more source
Factors Influencing Pap Smear Screening Uptake among Women Visiting Outpatient Clinics in Johor [PDF]
Introduction: Despite the benefits of cervical cancer screening, Pap smear uptake remains variable in Malaysia, with Johor previously reported as the state with the lowest uptake.
Suzane Shiyun Chin +5 more
doaj +1 more source

