Results 31 to 40 of about 31,217 (234)

Caplacizumab for immune thrombotic thrombocytopenic purpura: real-world multicenter data

open access: yesFrontiers in Medicine, 2023
Given the limited real-world data of caplacizumab, our multicenter real-world study was designed to assess the safety and efficacy of caplacizumab in immune thrombotic thrombocytopenic pupura (iTTP), compared to historic controls.
Eleni Gavriilaki   +25 more
doaj   +1 more source

L'évolution de l'église orthodoxe grecque dans l'agglomération bordelaise.

open access: yes, 2011
Cet historique de l'église orthodoxe grecque de Bordeaux (48 pages + photographies), présenté lors de la conférence organisée par "La mémoire de Bordeaux, de la communauté urbaine et de ses communes", le 24 novembre 2011, fut co-écrit par Vassilaki ...
Papanicolaou, Théodore   +1 more
core   +2 more sources

Usefulness of cytology and visual inspection with acetic acid in the detection of neoplastic lesions of the cervix at the Centro Médico Oncomujer during 2013-2014. Lima, Peru

open access: yesHorizonte Médico, 2017
Objective: To determine the usefulness of cytology and visual inspection with acetic acid in the detection of neoplastic lesions of the cervix. Materials and methods: An observational, retrospective, descriptive and cross-sectional study.
Manuel Jesús Rosado Flores   +3 more
doaj   +1 more source

Knowledge, perceptions and practice of cervical cancer prevention among female public secondary school teachers in Mushin local government area of Lagos State, Nigeria

open access: yesThe Pan African Medical Journal, 2017
INTRODUCTION: cervical cancer is the most common gynecological cancer and a leading cause of cancer death in women in Nigeria. This study was aimed to assess the knowledge, perception, and practice of cervical cancer prevention among female public ...
Mariam Adeola Toye   +5 more
doaj   +1 more source

The Role of Myocardial Strain Imaging in the Pre- and Post-Operative Assessment of Patients with Single Ventricle

open access: yesReviews in Cardiovascular Medicine, 2023
The term “single ventricle” refers to a wide range of cardiac structural and functional abnormalities which cause the morphologically right or left ventricle to be hypoplastic or functionally inadequate.
Panagiota Kleitsioti   +3 more
doaj   +1 more source

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

open access: yesAdvanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian   +14 more
wiley   +1 more source

Safety and Efficacy of Extracorporeal Photopheresis for Acute and Chronic Graft-versus-Host Disease

open access: yesPharmaceuticals
Background/Objectives: Despite novel biological agents, steroid-dependent or -refractory graft-versus-host disease (GvHD) remains a severe complication of allogeneic hematopoietic cell transplantation (allo-HCT).
Eleni Gavriilaki   +18 more
doaj   +1 more source

Targeted Genotyping of MIS-C Patients Reveals a Potential Alternative Pathway Mediated Complement Dysregulation during COVID-19 Infection

open access: yesCurrent Issues in Molecular Biology, 2022
Complement dysregulation has been documented in adults with COVID-19 and implicated in relevant pediatric inflammatory responses against SARS-CoV-2. We propose that signatures of complement missense coding SNPs associated with dysregulation could also be
Eleni Gavriilaki   +22 more
doaj   +1 more source

Epithelial SLC25A20 Deficiency Drives Immunosuppressive Neutrophil Remodeling via ARG1 Palmitoylation to Promote Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
SLC25A20 deficiency in tumor cells compromises mitochondrial LCFA transport, which suppresses FAO and drives compensatory release of palmitic acid‐enriched lipids into the TME. These tumor‐derived palmitic acids are taken up by TANs, promoting ZDHHC18‐catalyzed ARG1 palmitoylation.
Yue Han   +8 more
wiley   +1 more source

Safety and long-term efficacy of autologous hematopoietic cell transplantation for patients with systemic sclerosis

open access: yesFrontiers in Medicine
Autologous hematopoietic cell transplantation (HCT) has been introduced for patients with severe systemic sclerosis (SSc). We aimed to assess the safety and long-term efficacy of HCT modality for severe SSc, refractory to conventional therapy, in 17 ...
Eleni Gavriilaki   +16 more
doaj   +1 more source

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