Results 121 to 130 of about 80,855 (244)

Optimized iCIEF Fractionation Enables Deep Profiling of Antibody Drug Conjugate Charge Heterogeneity

ELECTROPHORESIS, EarlyView.
This study developed and optimized an iCIEF fractionation method to characterize ADC charge variants. The optimized approach enabled stable separation, identification of major PTMs, and drug‐load distributions across light and heavy chains. ABSTRACT Antibody drug conjugates (ADCs) are a novel class of therapeutic drugs that combine selectivity of an ...
Eunju Jang, Qunying Zhang, Paul M. Thomas   +2 more
wiley   +1 more source

Management of Bioprosthetic Valve Thrombosis Following Transcatheter Mitral Valve Replacement. [PDF]

JACC Case Rep
Davidson N, Murdoch D, Gurvitch R.
europepmc   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

Successful Balloon Valvuloplasty for Paravalvular Leak 4 Months After TAVR in a Bicuspid Aortic Valve. [PDF]

JACC Case Rep
Mosaad M, Algazlan S, Alshamardl K, Alsalman A, Omer H, Elneama A, Alghamedi M, Algathami A.   +7 more
europepmc   +1 more source

Design and Experimental Study of Pressure Maintenance and Temperature Control System for Hydrate Pressure Core Processing Device

Energy Science &Engineering, EarlyView.
This paper presents a hydrate pressure core processing device integrated with a high‐precision active control system to perform nondestructive transfer, cutting, and analysis. To address the limitations of slow dynamic response and high thermal inertia in traditional passive systems, a differentiated control scheme is implemented.
Liwen Nan, Jiawang Chen, Qiaoling Gao, Yingjie Liu   +3 more
wiley   +1 more source

Reliability assessment of key equipment for coal gasification using artificial intelligence technology. [PDF]

PLoS One
Wu L, Zhang Z, Ding R, Zhang W, Liu M.
europepmc   +1 more source

Experimental Study on the Combustion and Explosion Characteristics of Tributyl Phosphate and Kerosene Mixtures at Different Initial Pressures in High‐Temperature Environments

Energy Science &Engineering, EarlyView.
The explosion hazard of TBP and kerosene mixed vapor in the nuclear fuel reprocessing process is studied. The results enrich the explosion characteristics and explosion limits of TBP‐kerosene, and provide reference value and basis for the safety setting of the operation process and operating environment of nuclear fuel reprocessing plants ABSTRACT As ...
Pincong Wu, Xijing Li, Jing Luo, Yuchen Ouyang, Yuanzhi Li, Longfei Hou, Pengliang Li   +6 more
wiley   +1 more source

A monolithic patient-specific 3D-0D model for In silico investigation of hemodynamics in patients with left ventricular assist devices. [PDF]

Biomech Model Mechanobiol
Bonini M, Hirschvogel M, Ferguson M, Pagani F, Tang PC, Nordsletten D.   +5 more
europepmc   +1 more source

Hybrid Osprey‐Salp Swarm Optimization Algorithm for Single and Multiobjective Optimal Power Flow in Smart Grids With Renewable Energy Integration

Energy Science &Engineering, EarlyView.
The proposed hybrid osprey‐salp swarm optimization algorithm addresses optimal power flow (OPF) problems in smart grids incorporating solar, hydro, and thermal generators. The algorithm is validated on Institute of Electrical and Electronics Engineers 30‐, 57‐, and 118‐bus test systems across five single and multiobjective OPF scenarios.
Mujtaba Ali, Muhammad Yaqoob Javed, Aamer Bilal Asghar, Gang Xiong, Krzysztof Ejsmont, Xiaoli Liu   +5 more
wiley   +1 more source

What Will Define the Next Era of Transcatheter Aortic Valve Replacement: Cost, Volume, and Quality? [PDF]

JACC Asia
Iwata J, Hayashida K.
europepmc   +1 more source