Results 61 to 70 of about 25,372,263 (281)
Much focus is being dedicated to the development of innovative technologies for producing biodegradable polymers from plant biomass. It is proposed that annual and perennial herbaceous plants, such as miscanthus, be used as promising sources of cellulose.
Yulia Sevastyanova +13 more
doaj +1 more source
¿Qué es una ocurrencia? Sobre humanidades y ciencias
En primer término, se aborda la relación asimétrica de humanidades y ciencias en las instituciones contemporáneas de conocimiento sugiriendo la inconveniencia de acentuar la diferencia entre unas y otras, en la medida en que ambos órdenes epistémicos ...
Pablo Oyarzún
doaj +1 more source
Political Settlements: Issues paper [PDF]
Why do similar sets of formal institutions often have such divergent outcomes? An analysis of political settlements goes some way to answering this question by bringing into focus the contending interests that exist within any state, which constrain and ...
Di John, Jonathan, Putzel, James
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
This study presents a switch-mode assisted linear amplifier (SMALA) designed for use as a frequency-domain spectroscopy (FDS) excitation voltage source for the diagnostic testing of oil/paper insulation systems in large power transformers.
Shawn D. Nielsen +2 more
doaj +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source

