Results 71 to 80 of about 23,410,949 (245)
Empirical Transition Matrix of Multi-State Models: The etm Package [PDF]
Multi-State models provide a relevant framework for modelling complex event histories. Quantities of interest are the transition probabilities that can be estimated by the empirical transition matrix, that is also referred to as the Aalen-Johansen ...
Arthur Allignol +2 more
core +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
DTDA: An R Package to Analyze Randomly Truncated Data [PDF]
In this paper, the R package DTDA for analyzing truncated data is described. This package contains tools for performing three different but related algorithms to compute the nonparametric maximum likelihood estimator of the survival function in the ...
Carla Moreira +2 more
core +1 more source
Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung +190 more
wiley +1 more source
On Simulation of Manifold Indexed Fractional Gaussian Fields [PDF]
To simulate fractional Brownian motion indexed by a manifold poses serious numerical problems: storage, computing time and choice of an appropriate grid.
Alexandre Brouste +2 more
core +1 more source
Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang +7 more
wiley +1 more source
LogConcDEAD: An R Package for Maximum Likelihood Estimation of a Multivariate Log-Concave Density [PDF]
In this article we introduce the R package LogConcDEAD (Log-concave density estimation in arbitrary dimensions). Its main function is to compute the nonparametric maximum likelihood estimator of a log-concave density.
Madeleine Cule +2 more
core +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Structural Adaptive Smoothing in Diffusion Tensor Imaging: The R Package dti [PDF]
Diffusion weighted imaging has become and will certainly continue to be an important tool in medical research and diagnostics. Data obtained with diffusion weighted imaging are characterized by a high noise level.
Jörg Polzehl, Karsten Tabelow
core +1 more source