Results 71 to 80 of about 40,935,335 (372)
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
The Journal of Engineering, 2019 Near Infrared Spectroscopy (NIRS), as one of analysis technologies, has shown promisingly industrial applications for significant properties for recent decades such as fast response, preciseness, non-intrusion etc. Here, the authors employed NIRS coupled
Feng Tang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Tigger paper : integration [PDF]
, 2003 The process of architecture will always be holistic. As long as it is taught in segments, its educational structure will always run the risk of failing to meet this primary educational aim, and be continually shooting itself in the foot.
Angus, Michael, CEBE (Funder)
core
Proceedings of the National Academy of Sciences of the United States of America, 1979 We describe a technique for transferring electrophoretically separated bands of double-stranded DNA from agarose gels to diazobenzyloxymethyl-paper. Controlled cleavage of the DNA in situ by sequential treatment with dilute acid, which causes partial ...
G. Wahl +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Receipt from The Jerome Paper Co. [PDF]
, 1897 https://digitalcommons.salve.edu/goelet-new-york/1250/thumbnail ...
The Jerome Paper Co.
core +3 more sources
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source