Results 81 to 90 of about 40,935,335 (372)
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Optimising the number of channels in EEG-augmented image search [PDF]
Recent proof-of-concept research has appeared showing the applicability of Brain Computer Interface (BCI) technology in combination with the human visual system, to classify images.
Healy, Graham, Smeaton, Alan F.
core
Studia theodisca – Hölderliniana II (2016): Call for Papers.
openaire +3 more sources
Aid Networks and Mechanisms in a Migratory Context: Europe and the Middle East (1945-1970) International Writing Workshop - Paris, 3-5 December 2025 Organization : Alexandre Bibert (Deutsches Historisches Institut), Fabrice Jesné (Université de Nantes, CRHIA), Marie Levant (École française de Rome, Institut français du Proche-Orient).
openaire +2 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
On the flaming combustion of highly densified cypress cylindrical briquette of which diameter/length ratio is 1/2 in the high temperature air, it was reported that the flaming combustion duration is proportional to the product of the inverse square of ...
Hiroyuki ITO+3 more
doaj +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Tangent curve utilization for description of mechanical behaviour of pressed mixture
This article is focused on the utilization of tangent curve for description of mechanical behaviour of pressed mixture under compression loading. The aim of this experiment was to determine the general equation describing deformation characteristics of ...
D. Herák+3 more
doaj +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source