Results 281 to 290 of about 686,721 (344)

Quality Assessment of Box Materials for Long-Term Archival Storage: VOC Emissions Are Not a Significant Concern. [PDF]

Chempluschem
Deraz R, Di Gianvincenzo F, Schuhmann K, Anders M, Malešič J, Kralj Cigić I, Elnaggar A, Strlič M.   +7 more
europepmc   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

Daytime circadian patterns of exhaled volatile organic compounds in adults without and with type 1 and type 2 diabetes: protocol for an exploratory observational study. [PDF]

BMJ Open
Nicolier C, Rothenbühler M, Balmer ML, Witthauer L.   +3 more
europepmc   +1 more source

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

British Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins, Alan Wells, Nimish Patel, Nicole Muttera, Mattia Trunfio, Alessandra Manca, Amedeo De Nicolò, Micol Ferrara, Stefano Bonora, Jessica Cusato, Alice Palermiti, Antonio D'Avolio, Marissa Borochoff, Patricia K. Riggs, Elizabeth Hastie, Rabia S. Atayee, Stephanie Solso, Cheryl Dullano, Vanessa Gomez‐Moreno, Tara Tenenbaum, Robert Deiss, Davey M. Smith, Antoine Chaillon, Sara Gianella   +23 more
wiley   +1 more source

Systematic review of undeclared prohibited substances and pharmacological adulterants in dietary supplements: prevalence, detection, and risks in sport. [PDF]

Front Sports Act Living
Al-Saad N, Aljaal S, Alessa J, Santhosh ME.   +3 more
europepmc   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Outcompeting hydrofunctionalization: Asymmetric remote substitution of alkynes. [PDF]

Sci Adv
Shen YX, Ma C, Lin GQ, He ZT.
europepmc   +1 more source

Unlocking large-area free-standing MOF-glasses for molecular sieving gas separation membranes. [PDF]

Nat Commun
Smirnova O, Duval A, Komal A, Calderón Rodríguez L, Sajzew R, Schacher FH, Wondraczek L, Knebel A.   +7 more
europepmc   +1 more source

Competition for the conserved branch point sequence influences physiological outcomes in pre-mRNA splicing. [PDF]

Elife
Pereira de Castro KL, Abril JM, Liao KC, Hao H, Donohue JP, Russell WK, Fagg WS.   +6 more
europepmc   +1 more source

Pharmacokinetic Modeling of the "Nose-to-Brain" Pathway as Demonstrated by Intranasal Administration of Cannabidiol-Loaded Nanoparticles. [PDF]

Pharmaceuticals (Basel)
Eydelman I, Ben-Shabat S, Sintov AC.
europepmc   +1 more source