Results 41 to 50 of about 1,854,692 (262)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Legibility of Sans-Serif Typeface on Different Paper Grades Made from Invasive Alien Plant Species

open access: yesApplied Sciences
Invasive alien plant species (IAPS) may cause threats to native biodiversity in ecosystems. Researchers have been investigating all the possible ways that they can be used effectively for other purposes.
Klementina Možina   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The axiomatic properties of an entropy based index of segregation [PDF]

open access: yes, 2005
This paper reviews the properties suggested in the methodological literature on the measurement of occupational gender segregation. It is found that an index of (relative) segregation based on the entropy concept, IE, satisfies thirteen basic axioms ...
Mora, Ricardo, Ruiz-Castillo, Javier
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Status reports to the Paper Properties and Uses Project Advisory Committee

open access: yes, 1988
"October 19-20, 1988."Copy 2 includes slide material.Strength improvement and failure mechanisms: project 3469 / J. Waterhouse ; Internal strength enhancement: project 3526 / R. Stratton, K.
Dees, J.   +9 more
core  

An inverse application of unit cells for extracting fibre properties from effective properties of composites

open access: yes, 2023
A semi-analytical solution is obtained in this paper for the micromechanical analysis of the square and hexagonal unit cells using complex potentials. It provides a means of numerical characterisation of unidirectionally fibre-reinforced composites for ...
Zou, Zhenmin   +2 more
core   +1 more source

Valorization of Corn Stalk by the Production of Cellulose Nanofibers to Improve Recycled Paper Properties

open access: yesBioResources, 2016
Corn stalk, an agricultural waste, was valorized by the production of cellulose nanofibers (CNF), which were tested for improving recycled paper properties. CNF from eucalyptus kraft pulp (E-CNF) was used as a reference. Addition of 0.5% wt. CNF produced
Ana Balea   +6 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Status reports to the Paper Properties and Uses Project Advisory Committee

open access: yes, 1985
"October 22-23, 1985."Copy 2 includes handouts.Compressive strength: project 3469 / W.J. Whitsitt, J. F. Waterhouse ; Board properties and performance: project 3571 / W. J. Whitsitt, R. A. Halcomb ; Combined stress and failure processes: project 3500 / J.
Aziz, Salman   +9 more
core  

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