Integrated Genomic Characterization of Papillary Thyroid Carcinoma
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic alterations (relative to other carcinomas) and extended the set of known PTC driver ...
Nishant Agrawal +2 more
exaly +2 more sources
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma
W Marston Linehan +2 more
exaly +2 more sources
Differentiated Thyroid Cancer Genetic Mechanisms - Focus on Vitamin D Receptor and Methylenetetrahydrofolate Reductase Gene Polymorphisms [PDF]
Thyroid cancer is the most frequent endocrine cancer representing 1-1.5% of all cancers. Approximately 90% of these are differentiated thyroid carcinomas (DTC) with a favorable prognosis and cure rate.
Andra-Maria COCOLOS, Catalina POIANA
doaj +1 more source
Lactate Dehydrogenase A as a Potential New Biomarker for Thyroid Cancer [PDF]
Background Several cancers show increased levels of lactate dehydrogenase A (LDHA), which are associated with cancer progression. However, it remains unclear whether LDHA levels are associated with papillary thyroid cancer (PTC) aggressiveness or with ...
Eun Jeong Ban +8 more
doaj +1 more source
Molecular Correlates and Nuclear Features of Encapsulated Follicular-Patterned Thyroid Neoplasms [PDF]
Background Assessing nuclear features is diagnostically challenging in the aspect of thyroid pathology. The aim of this study was to determine whether pathologists could distinguish BRAF-like and RAS-like nuclear features morphologically and identify ...
Chan Kwon Jung +10 more
doaj +1 more source
The role of preoperative levels of serum IL-6, IL-8 and TNF-α and conventional inflammatory parameters in the detection of metastatic forms of papillary thyroid cancer [PDF]
Objective: Inflammation is an important part of cancer pathophysiology. Preoperative detection of inflammatory parameters like cytokines and conventional inflammatory parameters (CIP), as well as their correlation, could be helpful in early detection of ...
S. Hodzic-Redzic +3 more
doaj +1 more source
Patients after kidney transplantation have a much higher risk of developing malignant tumors than the general population. And the native kidney is an organ relatively susceptible to malignant tumors after renal transplantation.
Cheng Yi +9 more
doaj +1 more source
A Phase II Multi-Center, Non-Randomized, Parallel Group, Non-Inferiority Study to Compare the Efficacy of No Radioactive Iodine Remnant Ablation to Remnant Ablation Treatment in Low- to Intermediate-Risk of Papillary Thyroid Cancer: The MOREthyroid Trial Protocol [PDF]
Background Radioactive iodine (RAI) remnant ablation is recommended in patients with papillary thyroid cancer (PTC) and extrathyroidal extension or central lymph node metastasis.
Eun Kyung Lee +11 more
doaj +1 more source
PurposeTo assess the association of tumor architecture with cancer recurrence, metastasis, and cancer-specific survival (CSS) in patients treated with radical nephroureterectomy (RNU) for upper urinary tract urothelial carcinoma (UTUC) in Taiwan ...
Hui-Ying Liu +12 more
doaj +1 more source

