Results 171 to 180 of about 25,243 (199)

Brentuximab Vedotin With Adriamycin, Vinblastine, and Dacarbazine for Patients Aged 18–59 Years With Untreated Advanced Stage Classical Hodgkin Lymphoma: The Largest Real‐Life Series From Southern Italy Cancer Centers

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT BV + AVD is increasingly used for frontline treatment of stage III/IV cHL. Young adults and adults (Ya&A) were the most common patients treated with BV + AVD in clinical trials but have not been studied in non‐trial settings. We conducted a real‐life study in secondary and tertiary cancer centers to evaluate the PFS in 18–59 years aged ...
Marco Picardi   +28 more
wiley   +1 more source

CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression

open access: yesThe FEBS Journal, EarlyView.
CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson   +10 more
wiley   +1 more source

Cytomorphology of Warthin-like variant of papillary thyroid carcinoma

open access: hybrid, 2015
Murali Nirupama   +3 more
openalex   +1 more source

FGFR2 Fusions or Rearrangements in Young Intrahepatic and Perihilar Cholangiocarcinoma Patients: Key Genetic Insights From a Pan‐Asian Study

open access: yesHepatology Research, EarlyView.
FGFR2 Alterations in Young Adults with cholangiocarcinoma was common. Intrahepatic cholangiocarcinoma (ICC) is a rare liver cancer, typically seen in older adults. This study focused on younger patients across Asia, examining changes in the FGFR2 gene that may drive cancer growth.
Yuta Maruki   +22 more
wiley   +1 more source

Phosphoglycerate kinase 1 as a potential prognostic biomarker in papillary thyroid carcinoma [PDF]

open access: gold
Xiaoqing Shi   +10 more
openalex   +1 more source

To VAE or not to VAE: outcomes of radial scars/complex sclerosing lesions and papillary lesions without atypia in the King's College Hospital breast service (2017–2023)

open access: yesHistopathology, EarlyView.
Radial scars/complex sclerosing lesions (RS/CSL) without atypia have a low upgrade rate (1%) and could possibly be monitored radiologically, thus avoiding excision. Papillary lesions without atypia have a higher upgrade rate (4%) and should continue to undergo vacuum excision until we better understand these heterogeneous lesions.
Amy Llewellyn   +3 more
wiley   +1 more source

CDKN2A deletion in p16‐negative/HPV‐positive head and neck squamous cell carcinoma: Highlighting the molecular basis behind the limitation of relying on p16 immunohistochemistry as a surrogate marker for HPV involvement

open access: yesHistopathology, EarlyView.
We present a case series of HPV‐positive non‐keratinizing squamous cell carcinoma of the head and neck with discordant negative p16 staining due to CDKN2A deletion. These findings highlight the genomic basis behind the diagnostic pitfall of reliance on p16 immunohistochemistry as a surrogate marker of HPV and raise practice‐changing considerations for ...
Trevor Teich   +8 more
wiley   +1 more source

Pathologic assessment of resected stage III non‐small cell lung cancer after neoadjuvant chemotherapy: identification of additional prognostic factors

open access: yesHistopathology, EarlyView.
Multiple pathological variables are associated with prognosis in resected NSCLC at stage III undergoing neoadjuvant treatment, namely vascular, perineural and pleural infiltration, proliferation index, pathological response, fibrosis and presence of lymphocytes in the tumour bed.
Francesca Lunardi   +11 more
wiley   +1 more source

Correlation of unfavourable and favourable histology at radical prostatectomy with Decipher scores and freedom from biochemical recurrence

open access: yesHistopathology, EarlyView.
A recent study proposed a system of unfavourable and favourable histology categories to risk‐stratify prostate cancer patients. In a study of radical prostatectomy cases which had Decipher molecular classifier testing, unfavourable histology was associated with higher Decipher scores, increased biochemical recurrence (BCR) risk and improved BCR ...
Nancy Y Greenland   +9 more
wiley   +1 more source

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