Results 41 to 50 of about 75,135 (288)

gene polymorphism as a poor prognostic factor for papillary thyroid cancer

Tumor Biology, 2018
This is the first study to investigate the effect of vitamin D receptor ( VDR ) gene single-nucleotide polymorphisms on the clinicopathologic features of papillary thyroid cancer in Turkey.
Selvihan Beysel, Nilnur Eyerci, Ferda Alparslan Pinarli, Mahmut Apaydin, Muhammed Kizilgul, Mustafa Caliskan, Ozgur Ozcelik, Seyfullah Kan, Erman Cakal   +8 more
doaj   +1 more source

Papillary Thyroid Cancer in Struma Testis with Malignant Transformation in the Lung Associated with Trisomy 17 Successfully Treated with Total Thyroidectomy and Radioiodine Ablation

Case Reports in Oncology, 2014
Background: Struma testis is a rare entity, and there are only few reports on the malignant transformation of a testicular teratoma to papillary thyroid carcinoma in the literature.
Shadi Barakat, Jamie Odem, Jacqueline R. Batanian, Shahzad Raza, Uzma Z. Khan   +4 more
doaj   +1 more source

Metastatic diffuse follicular variant papillary thyroid cancer without cervical lymph node metastasis presenting with symptoms related to hypopituitarism

Einstein (São Paulo), 2023
In this article, we present a case of diffuse follicular variant papillary thyroid carcinoma with pituitary metastasis, which is a rare cause of pituitary metastasis.
Muhammed Kızılgül, Ömer Bayır, Bekir Uçan, Pınar Akhanlı, Hakan Düğer, Muhammed Erkam Sencar, Hayri Kertmen, Demet Yılmazer, Doğan Yazılıtaş, Güleser Saylam, Mehmet Hakan Korkmaz, Erman Çakal   +11 more
doaj   +1 more source

Be(a)ware of Leukocytosis in Papillary Thyroid Cancer

Case Reports in Endocrinology, 2022
Leukocytosis can be present at any time during various malignancies. A 42-year-old male was admitted to our department for surgical management of his metastatic papillary thyroid cancer. Persistent white blood cell (WBC) elevation with left shift led to a thorough investigation.
Styliani Laskou, Konstantinos Sapalidis, Christos Topalidis, Triantafyllia Koletsa, Isaak Kesisoglou   +4 more
openaire   +3 more sources

Evaluation of Proinflammatory Cytokine and Neopterin Levels in Women with Papillary Thyroid Carcinoma

The International Journal of Biological Markers, 2016
Introduction Papillary thyroid cancer is a disease that has been associated with chronic inflammation. The purpose of this study is to measure the production of the proinflammatory cytokines IL-1β, IL-6 and IL-8 and neopterin, which is a novel biomarker ...
Kemal Beksac MD, Cigdem Sonmez, Bahadir Cetin, Gorkem Kismali, Tevhide Sel, Yildirim Tuncer, Funda Kosova   +6 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

087. Relationship Between Neutrophil-Lymphocyte Ratio and Serum Thyroid Stimulating Hormone Preoperative Thyroidectomy as Predictors of Papillary Thyroid Cancer

JBN (Jurnal Bedah Nasional)
Background: Thyroid cancer is the most common endocrine malignancy. The incidence of papillary thyroid cancer has been increasing. Early diagnosis and management are crucial for thyroid cancer.
William Stevenson, Nico Lumintang, Sherly Tandililing, Windy Mariane Virenia Wariki   +3 more
doaj   +1 more source

Hashimoto's Thyroiditis and Papillary Thyroid Cancer [PDF]

Journal of Korean Thyroid Association, 2014
The association of Hashimoto’s thyroiditis (HT) with papillary thyroid cancer (PTC) has been still under debate. Some suggest that these two are positively correlated, whereas other studies report no relationship. We performed a systematic literature review of original studies to investigate the correlation between HT and PTC. The existing data provide
openaire   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Loss of Rap1GAP in Papillary Thyroid Cancer [PDF]

Molecular Endocrinology, 2009
Rap1 GTPase-activating protein (GAP) regulates the activity of Rap1, a putative oncogene. We previously reported Rap1GAP was highly expressed in normal human thyroid cells and decreased in five papillary thyroid carcinomas (PTCs).To confirm the significance of these findings, we analyzed Rap1GAP expression in a larger set of benign tumors (adenomas and
Anoma, Nellore, Karolina, Paziana, Changqing, Ma, Oxana M, Tsygankova, Yan, Wang, Kanchan, Puttaswamy, Ammarah U, Iqbal, Susanna R, Franks, Yu, Lv, Andrea B, Troxel, Michael D, Feldman, Judy L, Meinkoth, Marcia S, Brose   +12 more
openaire   +3 more sources