Results 61 to 70 of about 20,076 (210)

Clinical and Radiological Features Suggestive of Mucopolysaccharidosis in Two Siblings From Sudan: A Case Series

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Mucopolysaccharidosis should be suspected in patients presenting with multisystem involvement, including coarse facial features, skeletal abnormalities, and progressive organ dysfunction, particularly in resource‐limited settings where delayed diagnosis is common.
Alaa Bella, Mumen Abdalazim Dafallah, Ashraf Yousif Fadlalla, Bothaina Faisal Elmardi, Yomna Mohialdin Alataya, Abdalla Abdelmahmoud Abdalla, Mohammed Almeldin Ahmed Ibrahim, Mawada Faisal Nugud, Salah Elamin Ahmed Babiker, Hiba faroug Al_amin, Safaa Ayoub Yousif Mohammed, Moawia Elbalal Mohammed   +11 more
wiley   +1 more source

Unilateral Papilledema with Bilateral Optic Nerve Sheath Distension: A Case Report

Türk Oftalmoloji Dergisi
Bilateral edematous optic disc swelling from papilledema is caused by elevated intracranial pressure (ICP). Idiopathic intracranial hypertension (IIH), a clinical syndrome with elevated ICP of unclear etiology, is a frequent cause of this condition.
Raghda Shawky El-Gendy, Ahmad Shehata Abd El-Hamid, Ayman El-Sayed Ali Galhom, Nihal Adel Hassan, Ehab Mahmoud Ghoneim   +4 more
doaj   +1 more source

Safety considerations of gene‐based therapies for Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract Gene‐based therapies show increasing promise for the treatment of neurologic disease. In 2016, nusinersen, an RNA‐based therapy, was approved for children with spinal muscular atrophy (SMA). Over 200 clinical trials have utilized gene therapy approaches for a host of neurodegenerative and neuromuscular disorders, including Alzheimer's disease (
Elizabeth A. Bevins, Gabriel C. Léger, Michelle A. Herman, John M. Ringman, Subhojit Roy, Matthew Shtrahman, Judy Pa, Howard H. Feldman   +7 more
wiley   +1 more source

Crescentic “Semilunar” Cap‐Like Pus–Fluid Level in Bacterial‐Fungal Brain Abscess

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT A crescentic (“semilunar”) cap‐like pus–fluid level seen across CT/MRI sequences in a polymicrobial (bacterial‐fungal) brain abscess which may aid preoperative recognition when interpreted alongside clinical context and DWI/ADC.
Nazmin Ahmed, Mohammad Nazrul Hossain, Bipin Chaurasia   +2 more
wiley   +1 more source

Updates on ophthalmic imaging features of optic disc drusen, papilledema, and optic disc edema

Current Opinion in Neurology, 2020
Purpose of review Optic nerve head elevation can be associated with vision loss. This review provides an update regarding key features of optic disc drusen (ODD) compared with papilledema from increased intracranial pressure and optic disc edema from ...
Yan Yan, Y. J. Liao
semanticscholar   +1 more source

Immunophenotypic characteristics of plasma cells in POEMS syndrome

Cytometry Part B: Clinical Cytometry, Volume 110, Issue 4, Page 266-273, July 2026.
Abstract To analyze the immunophenotypic characteristics of plasma cells in patients with polyneuropathy, organomegaly, endocrinopathy, myeloma protein, and skin changes (POEMS) syndrome. This retrospective study included patients with POEMS syndrome hospitalized in the Department of Hematology, Huashan Hospital, from September 2017 to August 2025 ...
Zhenhua Wang, Tianling Ding, Beiqian Wu, Qiang Niu, Leyao Gu, Yan Yuan, Ping Zhu   +6 more
wiley   +1 more source

Peripapillary microperimetry and optical coherence tomography angiography in patients with optic disc edema

Journal of the Egyptian Ophthalmological Society
Purpose To compare the utility of peripapillary microperimetry and optical coherence tomography angiography (OCTA) in the differential diagnosis of patients with optic disc edema, including papilledema, optic neuritis, and anterior ischemic optic ...
Ghada A. Nassar, Ayman G. ElNahry, Mohammad R. AbouelFotouh, Aliaa A. Farag   +3 more
doaj   +1 more source

Hypertensive retinopathy in pre‐eclampsia and its association with disease severity and neonatal outcomes: A retrospective cohort study

International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 229-234, July 2026.
Abstract Introduction Pre‐eclampsia (PE) involves systemic endothelial dysfunction and microvascular injury, yet routine obstetric care lacks noninvasive readouts of maternal microvascular health. We evaluated whether hypertensive retinopathy (HR) detected during pregnancy is associated with maternal disease severity and adverse neonatal outcomes ...
Gabriele Saccone, Francesco Matarazzo, Mariarosaria Motta, Marika Rovetto, Michele Rinaldi, Maurizio Guida, Ciro Costagliola   +6 more
wiley   +1 more source

Optic Nerve Head Volumetry by Optical Coherence Tomography in Papilledema Related to Idiopathic Intracranial Hypertension

Translational Vision Science & Technology, 2020
Purpose Idiopathic intracranial hypertension (IIH) leads to optic nerve head swelling and optic atrophy if left untreated. We wanted to assess an easy to perform volumetric algorithm to detect and quantify papilledema in comparison to retinal nerve fiber
Michelle Dreesbach, L. Joachimsen, S. Küchlin, M. Reich, N. Gross, A. Brandt, F. Schuchardt, A. Harloff, D. Böhringer, W. Lagrèze   +9 more
semanticscholar   +1 more source

A 51‐year‐old female presenting with headache and vision loss

Headache: The Journal of Head and Face Pain, EarlyView.
Laurel Ovrom, Zachary Pardieck, Randy Christopher Bowen, Neena R. Cherayil   +3 more
wiley   +1 more source