High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
FEBS Open Bio, EarlyView.Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson +5 more
wiley +1 more source
Human papillomavirus genotyping among the women with cervical abnormalities in Ulaanbaatar, Mongolia [PDF]
, 2019 学位記番号 ...
TSEDENBAL, BATCHIMEG +2 more
core
Uptake of three doses of HPV vaccine by primary school girls in Eldoret, Kenya : a prospective cohort study in a malaria endemic setting [PDF]
, 2018 Background: All women are potentially at risk of developing cervical cancer at some point in their life, yet it is avoidable cause of death among women in Sub- Saharan Africa with a world incidence of 530,000 every year.
Kirop, Elijah +8 more
core +3 more sources
Immunosuppression Facilitates the Reactivation of Latent Papillomavirus Infections
Journal of Virology, 2013 At mucosal sites, papillomavirus genomes can persist in the epithelial basal layer following immune-mediated regression. Subsequent T-cell depletion stimulates a 3- to 5-log increase in the viral copy number, to levels associated with productive ...
G. Maglennon, P. McIntosh, J. Doorbar
semanticscholar +1 more source
Implementation of FTA Elute Card for Viral RNA Storage and Cost‐Effective Wastewater Surveillance
Advanced Sensor Research, EarlyView.A strategy is developed for room‐temperature storage of RNA from wastewater using FTA Elute cards, which allow for easy and portable transportation. FTA Elude cards provided a 15.4% recovery of the original RNA with cards, compared to only 0.5% recovery without cards.
Qingxin Hui +3 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen +7 more
wiley +1 more source
Human Papillomavirus and Associated Cancers: A Review
VirusesThe human papillomavirus is the most common sexually transmitted infection in the world. Most HPV infections clear spontaneously within 2 years of infection; however, persistent infection can result in a wide array of diseases, ranging from genital warts
J. E. Jensen +3 more
semanticscholar +1 more source
B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns
Advanced Science, EarlyView.B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang +16 more
wiley +1 more source
Human Papillomavirus Infection: Prevention, Barriers to Vaccination, and the Need for Education [PDF]
, 2016 While there is no known cure for HPV, prophylactic vaccination provides an effective method of primary prevention against HPV-related diseases. However, many females and males never receive the HPV vaccine as recommended.
Kessler, Theresa A
core +2 more sources
A Field‐Deployable RotEx‐LAMP‐LFA Platform for Molecular Triage of HPV‐Driven Oncogenesis
Advanced Science, EarlyView.This study presents RotEx‐LAMP‐LFA, a fully integrated, battery‐powered, low‐cost point‐of‐care device for rapid cervical cancer risk detection based on HPV16/18 E6/E7 mRNA. Clinically validated, the system demonstrated high sensitivity and specificity, and showed full concordance between self‐collected and clinician‐collected samples, offering a ...
Yuan Gao +10 more
wiley +1 more source