Results 31 to 40 of about 36,054 (205)

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Prophylactic human papillomavirus vaccines [PDF]

Journal of Clinical Investigation, 2006
Human papillomavirus (HPV) infection causes virtually all cases of cervical cancer, the second most common cause of death from cancer among women worldwide. This Review examines prophylactic HPV subunit vaccines based on the ability of the viral L1 capsid protein to form virus-like particles (VLPs) that induce high levels of neutralizing antibodies ...
Douglas R, Lowy, John T, Schiller
openaire   +2 more sources

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Influenza and Human Papillomavirus Vaccine Utilisation in Vulnerable Urban Youth in Edmonton, Alberta, Canada

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Introduction This project explores influenza and human papillomavirus (HPV) vaccine utilisation among a multi‐ethnic group of youth (aged 11–23 years) in Edmonton, Alberta, Canada. Method Using a cross‐sectional design and purposive sampling, influenza vaccine utilisation over 3 years was assessed via questionnaire.
Sarah Deck, Se Lim Jang, Rachel Harris, Fariba Kolahdooz, Moutasem Zakkar, Sangita Sharma   +5 more
wiley   +1 more source

Cervical human papillomavirus infection and squamous intraepithelial lesions in rural Gambia, West Africa: viral sequence analysis and epidemiology. [PDF]

, 2005
The development of effective strategies against cervical cancer in Africa requires accurate type specific data on human papillomavirus (HPV) prevalence, including determination of DNA sequences in order to maximise local vaccine efficacy.
Gelder, CM, S R Wall, Man, S, S Man, Walraven, G, Borysiewicz, Leszek K., Hart, Keith William, Fiander, AN, Man, Stephen Tzekwung, Scherf, C. F., C F Scherf, Morison, L., Walraven, G., C M Gelder, K W Hart, Fiander, Alison Nina, B West, Scherf, CF, Wall, SR, G Walraven, Borysiewicz, LK, Hart, KW, Gelder, C. M., Ekpo, G, L K Borysiewicz, G Ekpo, A N Fiander, Ekpo, G., Morison, L, L Morison, Wall, S. R., West, B, West, B.   +32 more
core   +1 more source

Decentralisation of the Healthcare Systems and the Functioning of Public Health Programmes in Single‐Party States: A Systematic Review

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Introduction Decentralisation is the transfer of authority from central to local governments, involving shared responsibilities in planning, management, and decision‐making. In public health, decentralisation might help improve service delivery by allowing local authorities to tailor interventions to the specific needs of diverse ...
Phonevilay Viphonephom, Ho Van Hoa, Sengchanh Kounnavong, Daniel Reinharz   +3 more
wiley   +1 more source

Parental Justifications for Not Vaccinating Children or Adolescents against Human Papillomavirus (HPV)

, 2023
Vaccination coverage against Human Papillomavirus (HPV) is low compared with uptake of other vaccines in many countries, including Brazil. The aim of this study was to examine the main reasons provided by parents or guardians of a target population that ...
Elisa D. T. Mendes, Eliza S. Rodrigues, Luciana B. Nucci   +2 more
core   +1 more source

Trends in the incidence of cancers of the breast and female genital tract in Harare, Zimbabwe 1990–2019

International Journal of Cancer, EarlyView.
What's New? Cancers of the breast and female genital tract represent more than half of all cancers in women in sub‐Saharan Africa. Here, the authors assessed incidence trends in a female population living in urban sub‐Saharan Africa based on the Zimbabwe National Cancer Registry in Harare over a 30‐year period.
Eric Chokunonga, Zvavahera Michael Chirenje, Margaret Borok, Rudo Makunike‐Mutasa, Ntokozo Ndlovu, Justice Mudavanhu, Biying Liu, D. Maxwell Parkin   +7 more
wiley   +1 more source

Stakeholders’ Understandings of Human Papillomavirus (HPV) Vaccination in Sub-Saharan Africa: A Rapid Qualitative Systematic Review

, 2021
Cervical cancer rates in Sub-Saharan Africa (SSA) are amongst the highest worldwide. All three of the Human Papillomavirus (HPV) vaccines (9-valent, quadrivalent and bivalent HPV vaccine) provide primary protection against the most common cancer-causing ...
Christopher J. Colvin, Alison Swartz, Caroline Deignan, Sara Cooper   +3 more
core   +1 more source