Results 41 to 50 of about 277,495 (235)

High Prevalence of HPV 51 in an Unvaccinated Population and Implications for HPV Vaccines [PDF]

, 2022
Human papillomavirus (HPV) is detected in 99.7% of cervical cancers. Current vaccines target types 16 and 18. Prior to vaccination implementation, a prospective cohort study was conducted to determine baseline HPV prevalence in unvaccinated women in ...
Kyrgiou, Maria, Ellis, Laura Burney, Laura Burney Ellis, Maria Kyrgiou, Bowden, Sarah J., Alison N. Fiander, Sarah J. Bowden, Bowden, Sarah, Hibbitts, Samantha, Samantha Hibbitts, Fiander, Alison N, Fiander, Alison N., Ellis, Laura   +12 more
core   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Designing of an mRNA vaccine against high-risk human papillomavirus targeting the E6 and E7 oncoproteins exploiting immunoinformatics and dynamic simulation.

PLoS ONE
Human papillomavirus 16 and human papillomavirus 18 have been associated with different life-threatening cancers, including cervical, lung, penal, vulval, vaginal, anal, and oropharyngeal cancers, while cervical cancer is the most prominent one.
Md Mijanur Rahman, Md Habib Ullah Masum, Rehana Parvin, Shuvo Chandra Das, Asma Talukder   +4 more
doaj   +1 more source

Obstacles to Implementing the HPV Vaccine: Is it Worth Pursuing or Not?

Asian Pacific Journal of Cancer Care, 2019
Cervical cancer, along with breast, colorectal, and lung cancer, has become increasingly problematic in Malaysia. The prevalence of cervical cancer in Malaysia is projected to rise in younger women, and Malaysia views this prediction with concern and ...
Mastura Mohd Sopian, Sharifah Azdiana Tuan Din, Hasmah Hussin   +2 more
doaj   +1 more source

An Update on Human Papilloma Virus Vaccines: History, Types, Protection, and Efficacy

Frontiers in Immunology, 2022
Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide. Early prevention with HPV vaccination is a safe and effective method against this disease.
Zahra Yousefi, Hamid Aria, Farhoodeh Ghaedrahmati, Tahereh Bakhtiari, Mahdieh Azizi, Reza Bastan, Reza Hosseini, Nahid Eskandari   +7 more
doaj   +1 more source

Regression of canine oral papillomas is associated with infiltration of CD4+ and CD8+ lymphocytes [PDF]

, 2001
Canine oral papillomavirus (COPV) infection is used in vaccine development against mucosal papillomaviruses. The predictable, spontaneous regression of the papillomas makes this an attractive system for analysis of cellular immunity.
Nicholls, Philip K., Parry, N.R., Gough, Gerald W., Anderson, Davina M., Gough, G.W., Stanley, M.A., Parry, Nigel R., Stanley, Margaret A., Nicholls, P.K., Moore, Peter F., Moore, Richard A., Moore, R.A., Anderson, D.M., Moore, P.F.   +13 more
core   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Human Papillomavirus Vaccination – A Moment of Prevention, a Lifetime of Protection

Indian Journal of Public Health
Human papillomavirus (HPV) vaccination is the primary preventive strategy to reduce the burden of cervical cancer as well as other HPV-related malignancies.
Priya Abraham
doaj   +1 more source

Governing HPV-related carcinoma using vaccines: Bottlenecks and breakthroughs

Frontiers in Oncology, 2022
Human papillomavirus (HPV) contributes to sexually transmitted infection, which is primarily associated with pre-cancerous and cancerous lesions in both men and women and is among the neglected cancerous infections in the world.
Rahul Bhattacharjee, Lamha Kumar, Archna Dhasmana, Tamoghni Mitra, Abhijit Dey, Sumira Malik, Bonglee Kim, Rohit Gundamaraju   +7 more
doaj   +1 more source

Purification of Disassembled Capsid Protein by Hydroxyapatite Chromatography Enhances Virus‐Like Particle Recovery

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Virus‐like particles (VLPs) are a promising modality with extensive applications in prophylactic and therapeutic vaccine design. Human Papillomavirus (HPV) vaccines are one such example where VLP vaccine applications have led to the successful reduction in HPV‐associated diseases, such as cervical cancer.
Nicholas Samuelson, Nathaniel Parker, Shiyi Wang, Sara Daley, Aaron Cote, Michael A. Winters   +5 more
wiley   +1 more source