Results 101 to 110 of about 1,357,951 (245)

Assessing Strengths and Limitations of Magnetoencephalography Source Imaging With Intracerebral EEG

Advanced Science, EarlyView.
Simultaneous MEG and stereotactic EEG (SEEG) recordings provide a direct validation framework for MEG source imaging in focal epilepsy. Virtual SEEG signals derived from MEG reconstructions reveal significant agreement with intracranial measures of spike localization, resting‐state oscillations, and functional connectivity, while also identifying ...
Jawata Afnan, Maria Fratello, Francesca Bonini, Samuel Medina Villalon, Zhengchen Cai, Jean‐Marc Lina, Jean‐Michel Badier, Fabrice Bartolomei, Jean Gotman, Christian G. Bénar, Christophe Grova   +10 more
wiley   +1 more source

CARACTERISTICA STĂRII FUNCŢIONALE A GLANDELOR ENDOCRINE ÎN DIABETUL EXPERIMENTAL PE FONDUL ADMINISTRĂRII EXTRASELOR DIN PRODUSE APICOLE

Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2016
Diabetul este o boală cronică metabolică având drept cauză deficitul primar de insulină absolută sau relativă şi se caracterizează prin perturbarea metabolismului predominant de carbohidraţi, toleranţă redusă la glucide, prezenţa glucozei în urină, fiind
Iulian PARA
doaj  

Pd‐Catalyzed Asymmetric Dearomative Heck/Tsuji‐Trost Difunctionalization of Naphthalenes

Advanced Science, EarlyView.
We have developed a palladium‐catalyzed asymmetric dearomative Heck/Tsuji‐Trost 1,4‐difunctionalization reaction of naphthalenes, affording 4‐aminospirocyclohexene oxindole products bearing two remote chiral centers. Through the effect of the newly designed chiral sulfinamide phosphine ligand with large steric hindrance, side reactions are inhibited ...
Long‐Ling Ma, Bing Xu, Junliang Zhang, Zhan‐Ming Zhang   +3 more
wiley   +1 more source

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

Advanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu, Ming Zhang, Yunxiang Feng, Yibo Deng, Kai Zhao, Xiangyu Li, Yun Lu, Li Tian, Tao Yang, Wei Yao, Jianming Wang, Zhengdong Deng   +11 more
wiley   +1 more source

Design and Engineering of an Artificial Bifunctional N‐Deacetylase/N‐Sulfotransferase for the Biosynthesis of N‐Sulfated Heparosan

Advanced Science, EarlyView.
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi, Ruirui Xu, Daoan Wang, Guobin Yin, Xinjing Wang, Haiqin Chen, Guocheng Du, Jian Chen, Zhen Kang   +8 more
wiley   +1 more source

Estudo de parâmetros de carcaça indicativos da produção de carne em machos leiteiros

Boletim de Indústria Animal, 2014
Ao proceder à avaliação das carcaças de 32 bovinos machos de origem leiteira, de graus de sangue variados (3/4 H.P,B. a P.O.), abatidos em grupos de oito aos 6, 12, 18 e 24 meses de idade, verificou-se que a quantidade total de carne da carcaça foi altamente correlacionada com as quantidades totais de carne de corte do antebraço, do corte do ...
Luciano Ricardo Marcondes da Silva, Pedro Biondi, Ernesto Augusto Nogueira de Freitas, Wallace Newton Scott, José Roberto Cosentino   +4 more
openaire   +8 more sources

Parámetros pronósticos en el tratamiento de la incontinencia fecal. ¿Es la sensibilidad a la electroestimulación anal una opción?

Revista de Cirugía Colorrectal
La incontinencia fecal (IF) es una afeccioÌÂÂÂn frecuente que puede afectar a la calidad de vida de los pacientes. La prevalencia global de la incontinencia está identificada hasta en el 7%. La estimulacioÌÂÂÂn eleÌÂÂÂctrica intraanal o transtibial son meÌÂÂÂtodos alternos utilizados previos a la electroestimulación sacra mediante un neuroestimulador ...
Carlos A. López-Bernal, Carolina Vázquez-Ãñiguez, Sharon J. Sánchez-Lara, Angie E. Vargas-Rodríguez, Jorge Garza-Sánchez, Mónica P. Hernández-Molina, Billy Jiménez-Bobadilla, Juan A. Villanueva-Herrero   +7 more
openaire   +2 more sources

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

Advanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu, Zhijun Qin, Jiapeng Yang, Baoyuan Zhang, Manqing Cao, Peng Wang, Zaiqi Wang, Jinghui Cheng, Lei Wang, Hong Liu, Hui Yang   +10 more
wiley   +1 more source

A qualitative content analysis exploring gender representation in language textbooks published by Jammu and Kashmir board of school education

Social Sciences and Humanities Open
This paper examines gender representation in Jammu and Kashmir Board of School Education (JKBOSE) language textbooks. These books were revised and developed as per the guidelines of National Curriculum Framework (NCF), 2005, which emphasizes on the ...
Shabir Ahmad Para
doaj   +1 more source

Tunable Reversible Photochromic Ultralong Organic Phosphorescence via a Universal Phenylpyridine Noncovalent Assembly Strategy

Advanced Science, EarlyView.
A concise supramolecular assembly strategy using α‐cyclodextrin and phenylpyridine derivatives affords dual‐functional materials with switchable multicolor photochromism and tunable ultralong organic phosphorescence, offering new platforms for various photonic applications. ABSTRACT Supramolecular photochromic materials capable of reversible alteration
Xue Bai, Renliang Wang, Hong‐Jin Xue, Zhuofan Jiang, Shuo Yang, Chiming Li, Yanqing Ge, Caihong Liu, Xian‐Yin Dai   +8 more
wiley   +1 more source