Results 201 to 210 of about 306,192 (264)

Microstructure and Property Modification of High-Strength Martensitic Steel Through Plasma Arc Remelting. [PDF]

open access: yesMaterials (Basel)
Liu Y   +13 more
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Protease-Activated Receptor-2 (PAR-2)-Related Peptides Induce Tear Secretion in Rats: Involvement of PAR-2 and Non-PAR-2 Mechanisms

The Journal of Pharmacology and Experimental Therapeutics, 2005
Protease-activated receptor-2 (PAR-2) plays an extensive role in the regulation of digestive exocrine secretion. The present study examined whether PAR-2-related peptides could modulate tear secretion in rats and analyzed the underlying mechanisms. SLIGRL-NH(2), a PAR-2-activating peptide (PAR-2-AP) derived from mouse/rat PAR-2, when administered i.v ...
Hiroyuki, Nishikawa   +9 more
openaire   +2 more sources

Increased mast cell expression of PAR‐2 in skin inflammatory diseases and release of IL‐8 upon PAR‐2 activation

Experimental Dermatology, 2010
Please cite this paper as: Increased mast cell expression of PAR‐2 in skin inflammatory diseases and release of IL‐8 upon PAR‐2 activation. Experimental Dermatology 2010; 19: 117–122. Abstract:  Mast cells are increasingly present in ...
Ricardo Filipe da Silva, Carvalho   +2 more
openaire   +2 more sources

Discovery of Potent and Selective Small-Molecule PAR-2 Agonists

Journal of Medicinal Chemistry, 2008
Proteinase activated receptor-2 plays a crucial role in a wide variety of conditions with a strong inflammatory component. We present the discovery and characterization of two structurally different, potent, selective, and metabolically stable small-molecule PAR-2 agonists.
Jimmi Gerner, Seitzberg   +8 more
openaire   +2 more sources

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