Results 201 to 210 of about 306,192 (264)
Kératodermie palmoplantaire héréditaire causée par des mutations du gène SERPINA12. [PDF]
Pan L, Bu Z.
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La ténectéplase pour la thrombolyse d’un AVC ischémique aigu chez une femme de 68 ans. [PDF]
Khan F +4 more
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Microstructure and Property Modification of High-Strength Martensitic Steel Through Plasma Arc Remelting. [PDF]
Liu Y +13 more
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The Journal of Pharmacology and Experimental Therapeutics, 2005
Protease-activated receptor-2 (PAR-2) plays an extensive role in the regulation of digestive exocrine secretion. The present study examined whether PAR-2-related peptides could modulate tear secretion in rats and analyzed the underlying mechanisms. SLIGRL-NH(2), a PAR-2-activating peptide (PAR-2-AP) derived from mouse/rat PAR-2, when administered i.v ...
Hiroyuki, Nishikawa +9 more
openaire +2 more sources
Protease-activated receptor-2 (PAR-2) plays an extensive role in the regulation of digestive exocrine secretion. The present study examined whether PAR-2-related peptides could modulate tear secretion in rats and analyzed the underlying mechanisms. SLIGRL-NH(2), a PAR-2-activating peptide (PAR-2-AP) derived from mouse/rat PAR-2, when administered i.v ...
Hiroyuki, Nishikawa +9 more
openaire +2 more sources
Experimental Dermatology, 2010
Please cite this paper as: Increased mast cell expression of PAR‐2 in skin inflammatory diseases and release of IL‐8 upon PAR‐2 activation. Experimental Dermatology 2010; 19: 117–122. Abstract: Mast cells are increasingly present in ...
Ricardo Filipe da Silva, Carvalho +2 more
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Please cite this paper as: Increased mast cell expression of PAR‐2 in skin inflammatory diseases and release of IL‐8 upon PAR‐2 activation. Experimental Dermatology 2010; 19: 117–122. Abstract: Mast cells are increasingly present in ...
Ricardo Filipe da Silva, Carvalho +2 more
openaire +2 more sources
Discovery of Potent and Selective Small-Molecule PAR-2 Agonists
Journal of Medicinal Chemistry, 2008Proteinase activated receptor-2 plays a crucial role in a wide variety of conditions with a strong inflammatory component. We present the discovery and characterization of two structurally different, potent, selective, and metabolically stable small-molecule PAR-2 agonists.
Jimmi Gerner, Seitzberg +8 more
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