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Toxicology, 2007
Parabens (p-hydroxybenzoate esters) are a group of widely used preservatives in topically applied cosmetic and pharmaceutical products. Parabens display weak associations with the estrogen receptors in vitro or in cell based models, but do exhibit estrogenic effects in animal models. It is our hypothesis that parabens exert their estrogenic effects, in
Jeffery J, Prusakiewicz +4 more
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Parabens (p-hydroxybenzoate esters) are a group of widely used preservatives in topically applied cosmetic and pharmaceutical products. Parabens display weak associations with the estrogen receptors in vitro or in cell based models, but do exhibit estrogenic effects in animal models. It is our hypothesis that parabens exert their estrogenic effects, in
Jeffery J, Prusakiewicz +4 more
openaire +2 more sources
Parabene und Verbraucherschutz
Nachrichten aus der ChemieAbstract In den 2000er Jahren tauchte auf vielen Körperpflegeprodukten das Etikett „parabenfrei“ auf. Die Kosmetikindustrie reagierte damit auf Befürchtungen der Medien und Verbraucher, Parabene könnten krank machen. Welche toxikologischen Daten gibt es, und wie bewerten Studien und Fachgremien das Gesundheitsrisiko?
Werner Lilienblum +2 more
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Archives of Dermatology, 1975
To the Editor.— In their Letter to the Editor concerning systemic eczematous "contact-type" dermatitis medicamentosa caused by parabens, Aeling and Nuss 1 report a paraben-sensitive individual whose dermatitis apparently was exacerbated following the injection of lidocaine (Xylocaine), which contains a paraben as a preservative.
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To the Editor.— In their Letter to the Editor concerning systemic eczematous "contact-type" dermatitis medicamentosa caused by parabens, Aeling and Nuss 1 report a paraben-sensitive individual whose dermatitis apparently was exacerbated following the injection of lidocaine (Xylocaine), which contains a paraben as a preservative.
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Solubility of Parabens in Alcohols
Journal of Pharmaceutical Sciences, 1969The solubilities of methyl, ethyl, propyl, and butyl parabens have been determined in a series of normal alcohols. This pure solvent scan indicated a dielectric requirement of about 14 for the subject compounds. Another dielectric requirement may be postulated to exist at a value of about 30.
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2015
Other regulatory bodies such as the U.S. FDA (Food and Drug Administration) have set the limit of methylparaben and propylparaben at 0.1% w/w. In cosmetics, the EEC and Danish cosmetic regulations give a combined maximum limit of 0.8% w/w for all the parabens.
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Other regulatory bodies such as the U.S. FDA (Food and Drug Administration) have set the limit of methylparaben and propylparaben at 0.1% w/w. In cosmetics, the EEC and Danish cosmetic regulations give a combined maximum limit of 0.8% w/w for all the parabens.
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Oral challenge with parabens in paraben‐sensitive patients
Contact Dermatitis, 1996N K, Veien, T, Hattel, G, Laurberg
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