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Topical Parabens: Benefits and Risks
Dermatology, 1977Parabens are the most frequently used preservative in dermatological medications. Some allergies have been reported to parabens, but these risks must be considered with respect to the benefits of parabens in concentrations used as preservatives in dermatological formulations.
O J, Lorenzetti, T C, Wernet
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JAMA, 1968
Paraben esters are incorporated in most dermatologic and cosmetic creams and lotions as preservatives. A two-year clinical study on the allergenic potential of these bacteriostatic and fungistatic chemicals showed that of 273 consecutive patients with chronic dermatitis who were routinely patch tested to 5% paraben in petrolatum had paraben allergy, an
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Paraben esters are incorporated in most dermatologic and cosmetic creams and lotions as preservatives. A two-year clinical study on the allergenic potential of these bacteriostatic and fungistatic chemicals showed that of 273 consecutive patients with chronic dermatitis who were routinely patch tested to 5% paraben in petrolatum had paraben allergy, an
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Toxicology, 2007
Parabens (p-hydroxybenzoate esters) are a group of widely used preservatives in topically applied cosmetic and pharmaceutical products. Parabens display weak associations with the estrogen receptors in vitro or in cell based models, but do exhibit estrogenic effects in animal models. It is our hypothesis that parabens exert their estrogenic effects, in
Jeffery J, Prusakiewicz +4 more
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Parabens (p-hydroxybenzoate esters) are a group of widely used preservatives in topically applied cosmetic and pharmaceutical products. Parabens display weak associations with the estrogen receptors in vitro or in cell based models, but do exhibit estrogenic effects in animal models. It is our hypothesis that parabens exert their estrogenic effects, in
Jeffery J, Prusakiewicz +4 more
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Parabene und Verbraucherschutz
Nachrichten aus der ChemieAbstract In den 2000er Jahren tauchte auf vielen Körperpflegeprodukten das Etikett „parabenfrei“ auf. Die Kosmetikindustrie reagierte damit auf Befürchtungen der Medien und Verbraucher, Parabene könnten krank machen. Welche toxikologischen Daten gibt es, und wie bewerten Studien und Fachgremien das Gesundheitsrisiko?
Werner Lilienblum +2 more
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Archives of Dermatology, 1975
To the Editor.— In their Letter to the Editor concerning systemic eczematous "contact-type" dermatitis medicamentosa caused by parabens, Aeling and Nuss 1 report a paraben-sensitive individual whose dermatitis apparently was exacerbated following the injection of lidocaine (Xylocaine), which contains a paraben as a preservative.
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To the Editor.— In their Letter to the Editor concerning systemic eczematous "contact-type" dermatitis medicamentosa caused by parabens, Aeling and Nuss 1 report a paraben-sensitive individual whose dermatitis apparently was exacerbated following the injection of lidocaine (Xylocaine), which contains a paraben as a preservative.
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Solubility of Parabens in Alcohols
Journal of Pharmaceutical Sciences, 1969The solubilities of methyl, ethyl, propyl, and butyl parabens have been determined in a series of normal alcohols. This pure solvent scan indicated a dielectric requirement of about 14 for the subject compounds. Another dielectric requirement may be postulated to exist at a value of about 30.
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Photocatalytic removal of parabens and halogenated products in wastewater: a review
Environmental Chemistry Letters, 2021Timothy O Ajiboye +2 more
exaly
2015
Other regulatory bodies such as the U.S. FDA (Food and Drug Administration) have set the limit of methylparaben and propylparaben at 0.1% w/w. In cosmetics, the EEC and Danish cosmetic regulations give a combined maximum limit of 0.8% w/w for all the parabens.
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Other regulatory bodies such as the U.S. FDA (Food and Drug Administration) have set the limit of methylparaben and propylparaben at 0.1% w/w. In cosmetics, the EEC and Danish cosmetic regulations give a combined maximum limit of 0.8% w/w for all the parabens.
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