Results 161 to 170 of about 30,499 (304)

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Multi‐Responsive Bowl‐Shaped Janus Nanomotors Based on Polyitaconic acid/Polypyrrole on the Surface of Iron Oxide Nanoparticles with Chemical, Electrical, and Magnetic Field Actuation for Targeted Drug Delivery Applications

Advanced NanoBiomed Research, EarlyView.
Bowl‐shaped Janus nanomotors with platinum, iron oxide, and polypyrrole integrate catalytic, magnetic, and electric propulsion for targeted drug delivery. They demonstrate controlled, directional motion under varying pH and hydrogen peroxide conditions, with optimal performance in neutral media.
Kimia Tavakoli Dehaghi, Sepideh Khoee, Shima Tavakoli, Oommen P. Varghese   +3 more
wiley   +1 more source

A gradient estimate for solutions to parabolic equations with discontinuous coefficients

Electronic Journal of Differential Equations, 2013
Li-Vogelius and Li-Nirenberg gave a gradient estimate for solutions of strongly elliptic equations and systems of divergence forms with piecewise smooth coefficients, respectively.
Jishan Fan, Kyoungsun Kim, Sei Nagayasu, Gen Nakamura   +3 more
doaj  

Optimal error estimates of the diffuse domain method for second order parabolic equations. [PDF]

BIT Numer Math
Hao W, Ju L, Xu Y.
europepmc   +1 more source

A bivariate Chebyshev spectral collocation quasilinearization method for nonlinear evolution parabolic equations. [PDF]

ScientificWorldJournal, 2014
Motsa SS, Magagula VM, Sibanda P.
europepmc   +1 more source

The Role of Intraparticle Diffusion in Kinetic Model Discrimination: Proof of Concept Testing for Methanol Dehydration

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The rate of a heterogeneous catalytic process may simultaneously be described by several rate equations. In this case, discrimination between the plausible kinetic models is required. An intrinsic kinetic model of a heterogeneous catalytic process may successively be discriminated by the transition from a reaction rate‐limited regime to an ...
Oleksii Zhokh, Andrii Trypolskyi, Peter Strizhak   +2 more
wiley   +1 more source

Resonant Tunneling in Laser‐Dressed Double‐Barrier Nanostructures: Role of Potential Geometry

Advanced Physics Research, EarlyView.
A schematic illustration of laser‐dressed double‐barrier nanostructures with rectangular, parabolic, and triangular potential profiles is presented. The intense laser field modifies the effective confinement potential, leading to a shift in resonance energies.
Recep Aydın, Mehmet Batı
wiley   +1 more source

Growth dynamics, skeletochronology, and histovariability of the theropod dinosaur Berthasaura leopoldinae

The Anatomical Record, EarlyView.
Osteohistological sampling on different bones of theropod dinosaur documents discrepant age record, growth, and metabolism. This could result unprecise paleobiological inferences if samplings are based on single bones. However, multi‐bone sampling can attenuate these discrepancies, helping to infer growth dynamics and physiology of these extinct ...
Geovane Alves de Souza, Marina Bento Soares, Luiz Carlos Weinschütz, Alexander Wilhelm Armin Kellner   +3 more
wiley   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source